Browsing FAS Scholarly Articles by Keyword "a multi-scale evolutionary model cell"
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Topology of Protein Interaction Network Shapes Protein Abundances and Strengths of Their Functional and Nonspecific Interactions
(Proceedings of the National Academy of Sciences, 2011)How do living cells achieve sufficient abundances of functional protein complexes while minimizing promiscuous nonfunctional interactions? Here we study this problem using a first-principle model of the cell whose phenotypic ...