Browsing FAS Scholarly Articles by Keyword "biosensors"

Now showing items 1-4 of 4

    • Conformational Control of Energy Transfer: A Mechanism for Biocompatible Nanocrystal-Based Sensors 

      Kay, Euan R.; Lee, Jungmin; Nocera, Daniel; Bawendi, Moungi G. (Wiley-Blackwell, 2012)
      Fold-up fluorophore: A new paradigm for designing self-referencing fluorescent nanosensors is demonstrated by interfacing a pH-triggered molecular conformational switch with quantum dots. Analytedependent, large-amplitude ...

    • An Engineered Calmodulin-Based Allosteric Switch for Peptide Biosensing 

      Meister, Glenna E.; Joshi, Neel S. (Wiley Blackwell (John Wiley & Sons), 2013)
      This work describes the development of a new platform for allosteric protein engineering that takes advantage of the ability of calmodulin to change conformation upon binding to peptide and protein ligands. The switch we ...

    • A general strategy to construct small molecule biosensors in eukaryotes 

      Feng, Justin; Jester, Benjamin W; Tinberg, Christine E; Mandell, Daniel J; Antunes, Mauricio S; Chari, Raj; Morey, Kevin J; Rios, Xavier; Medford, June I; Church, George M; Fields, Stanley; Baker, David (eLife Sciences Publications, Ltd, 2015)
      Biosensors for small molecules can be used in applications that range from metabolic engineering to orthogonal control of transcription. Here, we produce biosensors based on a ligand-binding domain (LBD) by using a method ...

    • A Guide to Fluorescent Protein FRET Pairs 

      Bajar, Bryce T.; Wang, Emily S.; Zhang, Shu; Lin, Michael Z.; Chu, Jun (MDPI, 2016)
      Förster or fluorescence resonance energy transfer (FRET) technology and genetically encoded FRET biosensors provide a powerful tool for visualizing signaling molecules in live cells with high spatiotemporal resolution. ...