Now showing items 1-5 of 5

    • All-Optical Interrogation of Neural Circuits 

      Emiliani, V.; Cohen, Adam Ezra; Deisseroth, K.; Hausser, M. (Society for Neuroscience, 2015)
      There have been two recent revolutionary advances in neuroscience: First, genetically encoded activity sensors have brought the goal of optical detection of single action potentials in vivo within reach. Second, optogenetic ...
    • Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans 

      Narayan, Anusha; Venkatachalam, Vivek; Durak, Omer; Reilly, Douglas K.; Bose, Neelanjan; Schroeder, Frank C.; Samuel, Aravinthan DT; Srinivasan, Jagan; Sternberg, Paul W. (Proceedings of the National Academy of Sciences, 2016)
      Animals find mates and food, and avoid predators, by navigating to regions within a favorable range of available sensory cues. How are these ranges set and recognized? Here we show that male Caenorhabditis elegans exhibit ...
    • Distinct Spatiotemporal Activity in Principal Neurons of the Mouse Olfactory Bulb in Anesthetized and Awake States 

      Blauvelt, David Gregory; Sato, Tomokazu F.; Wienisch, Martin; Murthy, Venkatesh N. (Frontiers Media S.A., 2013)
      The acquisition of olfactory information and its early processing in mammals are modulated by brain states through sniffing behavior and neural feedback. We imaged the spatiotemporal pattern of odor-evoked activity in a ...
    • Pan-neuronal imaging in roaming Caenorhabditis elegans 

      Venkatachalam, Vivek; Ji, Ni; Wang, Xian-Ling; Clark, Christopher Luce; Mitchell, James Kameron; Klein, Mason Joseph; Tabone, Christopher; Florman, Jeremy; Ji, Hongfei; Greenwood, Joel S.f.; Chisholm, Andrew; Srinivasan, Jagan; Alkema, Mark; Zhen, Mei; Samuel, Aravinthan DT (Proceedings of the National Academy of Sciences, 2015)
      We present an imaging system for pan-neuronal recording in crawling Caenorhabditis elegans. A spinning disk confocal microscope, modified for automated tracking of the C. elegans head ganglia, simultaneously records the ...
    • Sensory determinants of behavioral dynamics in Drosophila thermotaxis 

      Klein, Mason Joseph; Afonso, Bruno; Vonner, Ashley James; Hernandez-Nunez, Luis; Berck, Matthew E; Tabone, Christopher; Kane, Elizabeth Anne; Pieribone, Vincent A.; Nitabach, Michael N.; Cardona, Albert; Zlatic, Marta; Sprecher, Simon G.; Gershow, Marc; Garrity, Paul A.; Samuel, Aravinthan DT (Proceedings of the National Academy of Sciences, 2014)
      Complex animal behaviors are built from dynamical relationships between sensory inputs, neuronal activity, and motor outputs in patterns with strategic value. Connecting these patterns illuminates how nervous systems compute ...