Browsing FAS Scholarly Articles by Keyword "dual-specificity tyrosine-regulated kinase signaling"
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The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells
(eLife Sciences Publications, Ltd, 2015)The balance between Th17 and T regulatory (Treg) cells critically modulates immune homeostasis, with an inadequate Treg response contributing to inflammatory disease. Using an unbiased chemical biology approach, we identified ...