Browsing FAS Scholarly Articles by Keyword "experimental evolution"
Now showing items 1-6 of 6
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Crowded growth leads to the spontaneous evolution of semistable coexistence in laboratory yeast populations
(Proceedings of the National Academy of Sciences, 2015)Identifying the mechanisms that create and maintain biodiversity is a central challenge in biology. Stable diversification of microbial populations often requires the evolution of differences in resource utilization. ... -
The Fates of Mutant Lineages and the Distribution of Fitness Effects of Beneficial Mutations in Laboratory Budding Yeast Populations
(Genetics Society of America, 2014)The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting microbial populations, this process is particularly hard to predict because lineages with different beneficial mutations often ... -
Genetic Variation and the Fate of Beneficial Mutations in Asexual Populations
(Genetics Society of America, 2011)The fate of a newly arising beneficial mutation depends on many factors, such as the population size and the availability and fitness effects of other mutations that accumulate in the population. It has proven difficult ... -
Improved Use of a Public Good Selects for the Evolution of Undifferentiated Multicellularity
(eLife Sciences Publications, Ltd, 2013)We do not know how or why multicellularity evolved. We used the budding yeast, Saccharomyces cerevisiae, to ask whether nutrients that must be digested extracellularly select for the evolution of undifferentiated ... -
An Integrative Approach to Understanding Microbial Diversity: From Intracellular Mechanisms to Community Structure
(Blackwell Publishing Ltd., 2010)Trade-offs have been put forward as essential to the generation and maintenance of diversity. However, variation in trade-offs is often determined at the molecular level, outside the scope of conventional ecological inquiry. ... -
Stress-response balance drives the evolution of a network module and its host genome
(John Wiley & Sons, Ltd, 2015)Stress response genes and their regulators form networks that underlie drug resistance. These networks often have an inherent tradeoff: their expression is costly in the absence of stress, but beneficial in stress. They ...