• Login
Search 
  • DASH Home
  • Faculty of Arts and Sciences
  • FAS Scholarly Articles
  • Search
  • DASH Home
  • Faculty of Arts and Sciences
  • FAS Scholarly Articles
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Browse

All of DASH
  • Communities & Collections
  • By Issue Date
  • Author
  • Title
  • Keyword
  • FAS Department
This Collection
  • By Issue Date
  • Author
  • Title
  • Keyword
  • FAS Department

Submitters

  • Login
  • Quick submit
  • Waiver Generator

Filter

Author
  • Marx, Christopher J (4)
  • Aziz, Michael (3)
  • Gordon, Roy (3)
  • Mahadevan, Lakshminarayanan (3)
  • Saghatelian, Alan (3)
  • Aizenberg, Joanna (2)
  • Biewener, Andrew (2)
  • Clardy, Jon (2)
  • Delaney, Nigel Francis (2)
  • Estrada, Javier (2)
  • ... View More
Keyword
  • Biochemistry$:$ (79)
  • Biology and Life Sciences (36)
  • Proteins (29)
  • Genetics (25)
  • Cell Biology (22)
  • Medicine and Health Sciences (21)
  • Biology (20)
  • Microbiology (16)
  • Physical Sciences (16)
  • Biology and life sciences (15)
  • ... View More
FAS Department
  • Chemistry and Chemical Biology (9)
  • Engineering and Applied Sciences (9)
  • Organismic and Evolutionary Biology (9)
  • Molecular and Cellular Biology (6)
  • Other Research Unit (2)
  • Physics (2)
Date Issued
  • 2020 - 2021 (3)
  • 2010 - 2019 (75)
  • 2009 - 2009 (1)

About

  • About DASH
  • DASH Stories
  • DASH FAQs
  • Accessibility
  • COVID-related Research
  • Terms of Use
  • Privacy Policy

Statistics

  • By Schools
  • By Collections
  • By Departments
  • By Items
  • By Country
  • By Authors

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 1-10 of 79

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100
Thumbnail

The Drosophila melanogaster PeptideAtlas facilitates the use of peptide data for improved fly proteomics and genome annotation 

Loevenich, Sandra N; Brunner, Erich; King, Nichole L; Deutsch, Eric W; Stein, Stephen E; Aebersold, Ruedi; Hafen, Ernst (Springer Science and Business Media LLC, 2009-02-11)
Background: Crucial foundations of any quantitative systems biology experiment are correct genome and proteome annotations. Protein databases compiled from high quality empirical protein identifications that are in turn ...
Thumbnail

Mapping the Fitness Landscape of Gene Expression Uncovers the Cause of Antagonism and Sign Epistasis between Adaptive Mutations 

Chou, Hsin-Hung; Delaney, Nigel F.; Draghi, Jeremy A.; Marx, Christopher J. (Public Library of Science, 2014)
How do adapting populations navigate the tensions between the costs of gene expression and the benefits of gene products to optimize the levels of many genes at once? Here we combined independently-arising beneficial ...
Thumbnail

The Role of Muscle microRNAs in Repairing the Neuromuscular Junction 

Valdez, Gregorio; Heyer, Mary P.; Feng, Guoping; Sanes, Joshua R. (Public Library of Science, 2014)
microRNAs have been implicated in mediating key aspects of skeletal muscle development and responses to diseases and injury. Recently, we demonstrated that a synaptically enriched microRNA, miR-206, functions to promote ...
Thumbnail

Deletion of Prepl Causes Growth Impairment and Hypotonia in Mice 

Lone, Anna Mari; Leidl, Mathias; McFedries, Amanda K.; Horner, James W.; Creemers, John; Saghatelian, Alan (Public Library of Science, 2014)
Genetic studies of rare diseases can identify genes of unknown function that strongly impact human physiology. Prolyl endopeptidase-like (PREPL) is an uncharacterized member of the prolyl peptidase family that was discovered ...
Thumbnail

A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests 

Schroeder, Frederick A.; Lewis, Michael C.; Fass, Daniel M.; Wagner, Florence F.; Zhang, Yan-Ling; Hennig, Krista M.; Gale, Jennifer; Zhao, Wen-Ning; Reis, Surya; Barker, Douglas D.; Berry-Scott, Erin; Kim, Sung Won; Clore, Elizabeth L.; Hooker, Jacob M.; Holson, Edward B.; Haggarty, Stephen J.; Petryshen, Tracey L. (Public Library of Science, 2013)
Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade. Pharmacotherapy, the primary – albeit often ineffective – treatment ...
Thumbnail

Shifts in the Distribution of Mass Densities Is a Signature of Caloric Restriction in Caenorhabditis elegans 

Reina, Alfonso; Subramaniam, Anand Bala; Laromaine, Anna; Samuel, Aravinthan D. T.; Whitesides, George M. (Public Library of Science, 2013)
Although the starvation response of the model multicellular organism Caenorhabditis elegans is a subject of much research, there is no convenient phenotypic readout of caloric restriction that can be applicable to large ...
Thumbnail

Metabolic Erosion Primarily Through Mutation Accumulation, and Not Tradeoffs, Drives Limited Evolution of Substrate Specificity in Escherichia coli 

Leiby, Nicholas; Marx, Christopher J. (Public Library of Science, 2014)
Evolutionary adaptation to a constant environment is often accompanied by specialization and a reduction of fitness in other environments. We assayed the ability of the Lenski Escherichia coli populations to grow on a range ...
Thumbnail

Caveolin-1 Is a Critical Determinant of Autophagy, Metabolic Switching, and Oxidative Stress in Vascular Endothelium 

Shiroto, Takashi; Romero, Natalia; Sugiyama, Toru; Sartoretto, Juliano L.; Kalwa, Hermann; Yan, Zhonghua; Shimokawa, Hiroaki; Michel, Thomas (Public Library of Science, 2014)
Caveolin-1 is a scaffolding/regulatory protein that interacts with diverse signaling molecules. Caveolin-1null mice have marked metabolic abnormalities, yet the underlying molecular mechanisms are incompletely understood. ...
Thumbnail

The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum 

Harcombe, William R.; Delaney, Nigel F.; Leiby, Nicholas; Klitgord, Niels; Marx, Christopher J. (Public Library of Science, 2013)
The most powerful genome-scale framework to model metabolism, flux balance analysis (FBA), is an evolutionary optimality model. It hypothesizes selection upon a proposed optimality criterion in order to predict the set of ...
Thumbnail

A Sexually Conditioned Switch of Chemosensory Behavior in C. elegans 

Sakai, Naoko; Iwata, Ryo; Yokoi, Saori; Butcher, Rebecca A.; Clardy, Jon; Tomioka, Masahiro; Iino, Yuichi (Public Library of Science, 2013)
In sexually reproducing animals, mating is essential for transmitting genetic information to the next generation and therefore animals have evolved mechanisms for optimizing the chance of successful mate location. In the ...
  • 1
  • 2
  • 3
  • 4
  • . . .
  • 8

Filter

Author
  • Marx, Christopher J (4)
  • Aziz, Michael (3)
  • Gordon, Roy (3)
  • Mahadevan, Lakshminarayanan (3)
  • Saghatelian, Alan (3)
  • Aizenberg, Joanna (2)
  • Biewener, Andrew (2)
  • Clardy, Jon (2)
  • Delaney, Nigel Francis (2)
  • Estrada, Javier (2)
  • ... View More
Keyword
  • Biochemistry$:$ (79)
  • Biology and Life Sciences (36)
  • Proteins (29)
  • Genetics (25)
  • Cell Biology (22)
  • Medicine and Health Sciences (21)
  • Biology (20)
  • Microbiology (16)
  • Physical Sciences (16)
  • Biology and life sciences (15)
  • ... View More
FAS Department
  • Chemistry and Chemical Biology (9)
  • Engineering and Applied Sciences (9)
  • Organismic and Evolutionary Biology (9)
  • Molecular and Cellular Biology (6)
  • Other Research Unit (2)
  • Physics (2)
Date Issued
  • 2020 - 2021 (3)
  • 2010 - 2019 (75)
  • 2009 - 2009 (1)

e: osc@harvard.edu

t: +1 (617) 495 4089

Creative Commons license‌Creative Commons Attribution 4.0 International License

Except where otherwise noted, this work is subject to a Creative Commons Attribution 4.0 International License, which allows anyone to share and adapt our material as long as proper attribution is given. For details and exceptions, see the Harvard Library Copyright Policy ©2022 Presidents and Fellows of Harvard College.

  • Follow us on Twitter
  • Contact
  • Harvard Library
  • Harvard University