Race Differences in the Association between Multivitamin Exposure and Wheezing in Preterm Infants
Hibbs, Anna Maria
Babineau, Denise C.
MetadataShow full item record
CitationHibbs, Anna Maria, Denise C. Babineau, Xuelei Wang, and Susan Redline. 2014. “Race Differences in the Association between Multivitamin Exposure and Wheezing in Preterm Infants.” Journal of perinatology : official journal of the California Perinatal Association 35 (3): 192-197. doi:10.1038/jp.2014.176. http://dx.doi.org/10.1038/jp.2014.176.
AbstractObjective: We aimed to determine whether vitamin D exposure, as estimated by use of multivitamins, is positively or negatively associated with recurrent wheezing in infants born preterm. Study Design This prospective cohort study enrolled 300 infants, born at 28 0/7– 34 6/7 weeks gestational age, and conducted follow-up at 3, 6, 9, and 12 months adjusted age. Results: 55.9% of black and 36.6% of non-black infants experienced recurrent wheezing. Adjusted odds ratios for the association between multivitamin exposure at 3 months and recurrent wheezing were 2.15 (95% CI: 0.97, 4.75) for black and 0.43 (95% CI: 0.19, 0.96) for non-black infants with an interaction by race (p=0.003). In lag-effect models, odds ratios were 2.69 (95% CI: 1.41, 5.14) for black and 0.50 (95% CI: 0.27, 0.92) for non-black infants. Conclusions: Differences by race were seen in associations between multivitamins and wheezing; population heterogeneity should be considered when evaluating vitamin supplementation.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:22856876