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dc.contributor.authorWarner, Freda M.en_US
dc.contributor.authorCragg, Jacquelyn J.en_US
dc.contributor.authorWeisskopf, Marc G.en_US
dc.contributor.authorKramer, John K.en_US
dc.date.accessioned2015-10-01T14:55:47Z
dc.date.issued2015en_US
dc.identifier.citationWarner, Freda M., Jacquelyn J. Cragg, Marc G. Weisskopf, and John K. Kramer. 2015. “Spinal Cord Injury and Migraine Headache: A Population-Based Study.” PLoS ONE 10 (8): e0135550. doi:10.1371/journal.pone.0135550. http://dx.doi.org/10.1371/journal.pone.0135550.en
dc.identifier.issn1932-6203en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:22856895
dc.description.abstractMigraine headaches are a common neurological condition, negatively impacting health and quality of life. Among potential risk factors for migraine headache, risk of migraine headaches was elevated in individuals with spinal cord injury (SCI). The association between migraines and SCI is intriguing to consider from the perspective that migraine headaches may be acquired in response to damage in the spinal cord. The primary objective of this study was to further examine the association between SCI and migraine headache, controlling for potential confounding variables. A secondary objective was to determine the impact of migraine headaches on self-perceived health. Data from a sample of 61,047 participants were obtained from the cross-sectional Canadian Community Health Survey. Multivariable logistic regression was used to explore the association between SCI and migraine headache using probability weights and adjusting for confounders. The multivariable age- and sex-adjusted model revealed a strong association between SCI and migraine headache, with an adjusted odds ratio for migraine of 4.82 (95% confidence interval [3.02, 7.67]) among those with SCI compared to those without SCI. Further, individuals who experienced both SCI and migraine tended to report poorer perceived general health compared with the other groups (i.e., SCI and no migraine). In conclusion, this study established a strong association between SCI and migraine headache. Further research is needed to explore the possible mechanisms underlying this relationship. Improvements in clinical practice to minimize this issue could result in significant improvements in quality of life.en
dc.language.isoen_USen
dc.publisherPublic Library of Scienceen
dc.relation.isversionofdoi:10.1371/journal.pone.0135550en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550273/pdf/en
dash.licenseLAAen_US
dc.titleSpinal Cord Injury and Migraine Headache: A Population-Based Studyen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalPLoS ONEen
dash.depositing.authorWeisskopf, Marc G.en_US
dc.date.available2015-10-01T14:55:47Z
dc.identifier.doi10.1371/journal.pone.0135550*
dash.contributor.affiliatedWeisskopf, Marc


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