Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate

DSpace/Manakin Repository

Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate

Show simple item record

dc.contributor.author Wang, Xiaoling en_US
dc.contributor.author Wang, Guoqing en_US
dc.contributor.author Hao, Mudong en_US
dc.date.accessioned 2015-10-01T14:56:24Z
dc.date.issued 2015 en_US
dc.identifier.citation Wang, Xiaoling, Guoqing Wang, and Mudong Hao. 2015. “Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate.” Computational and Mathematical Methods in Medicine 2015 (1): 581829. doi:10.1155/2015/581829. http://dx.doi.org/10.1155/2015/581829. en
dc.identifier.issn 1748-670X en
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:22856921
dc.description.abstract Bacterial biofilms are organized communities composed of millions of microorganisms that accumulate on almost any kinds of surfaces. In this paper, a biofilm growth model on an agar substrate is developed based on mass conservation principles, Fick's first law, and Monod's kinetic reaction, by considering nutrient diffusion between biofilm and agar substrate. Our results show biofilm growth evolution characteristics such as biofilm thickness, active biomass, and nutrient concentration in the agar substrate. We quantitatively obtain biofilm growth dependence on different parameters. We provide an alternative mathematical method to describe other kinds of biofilm growth such as multiple bacterial species biofilm and also biofilm growth on various complex substrates. en
dc.language.iso en_US en
dc.publisher Hindawi Publishing Corporation en
dc.relation.isversionof doi:10.1155/2015/581829 en
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556878/pdf/ en
dash.license LAA en_US
dc.title Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate en
dc.type Journal Article en_US
dc.description.version Version of Record en
dc.relation.journal Computational and Mathematical Methods in Medicine en
dash.depositing.author Wang, Xiaoling en_US
dc.date.available 2015-10-01T14:56:24Z

Files in this item

Files Size Format View
4556878.pdf 1.179Mb PDF View/Open

This item appears in the following Collection(s)

Show simple item record

 
 

Search DASH


Advanced Search
 
 

Submitters