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dc.contributor.authorWang, Xiaolingen_US
dc.contributor.authorWang, Guoqingen_US
dc.contributor.authorHao, Mudongen_US
dc.date.accessioned2015-10-01T14:56:24Z
dc.date.issued2015en_US
dc.identifier.citationWang, Xiaoling, Guoqing Wang, and Mudong Hao. 2015. “Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate.” Computational and Mathematical Methods in Medicine 2015 (1): 581829. doi:10.1155/2015/581829. http://dx.doi.org/10.1155/2015/581829.en
dc.identifier.issn1748-670Xen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:22856921
dc.description.abstractBacterial biofilms are organized communities composed of millions of microorganisms that accumulate on almost any kinds of surfaces. In this paper, a biofilm growth model on an agar substrate is developed based on mass conservation principles, Fick's first law, and Monod's kinetic reaction, by considering nutrient diffusion between biofilm and agar substrate. Our results show biofilm growth evolution characteristics such as biofilm thickness, active biomass, and nutrient concentration in the agar substrate. We quantitatively obtain biofilm growth dependence on different parameters. We provide an alternative mathematical method to describe other kinds of biofilm growth such as multiple bacterial species biofilm and also biofilm growth on various complex substrates.en
dc.language.isoen_USen
dc.publisherHindawi Publishing Corporationen
dc.relation.isversionofdoi:10.1155/2015/581829en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556878/pdf/en
dash.licenseLAAen_US
dc.titleModeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrateen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalComputational and Mathematical Methods in Medicineen
dash.depositing.authorWang, Xiaolingen_US
dc.date.available2015-10-01T14:56:24Z
dc.identifier.doi10.1155/2015/581829*
dash.authorsorderedfalse
dash.contributor.affiliatedWang, Xiaoling


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