Drug Induced Liver Injury: Review with a Focus on Genetic Factors, Tissue Diagnosis, and Treatment Options

DSpace/Manakin Repository

Drug Induced Liver Injury: Review with a Focus on Genetic Factors, Tissue Diagnosis, and Treatment Options

Citable link to this page

 

 
Title: Drug Induced Liver Injury: Review with a Focus on Genetic Factors, Tissue Diagnosis, and Treatment Options
Author: Khoury, Tawfik; Rmeileh, Ayman Abu; Yosha, Liron; Benson, Ariel A.; Daher, Saleh; Mizrahi, Meir

Note: Order does not necessarily reflect citation order of authors.

Citation: Khoury, Tawfik, Ayman Abu Rmeileh, Liron Yosha, Ariel A. Benson, Saleh Daher, and Meir Mizrahi. 2015. “Drug Induced Liver Injury: Review with a Focus on Genetic Factors, Tissue Diagnosis, and Treatment Options.” Journal of Clinical and Translational Hepatology 3 (2): 99-108. doi:10.14218/JCTH.2015.00007. http://dx.doi.org/10.14218/JCTH.2015.00007.
Full Text & Related Files:
Abstract: Drug-induced liver injury (DILI) is a rare but potentially life threatening adverse drug reaction. DILI may mimic any morphologic characteristic of acute or chronic liver disease, and the histopathologic features of DILI may be indistinguishable from those of other causes of liver injury, such as acute viral hepatitis. In this review article, we provide an update on causative agents, clinical features, pathogenesis, diagnosis modalities, and outcomes of DILI. In addition, we review results of recently reported genetic studies and updates on pharmacological and invasive treatments.
Published Version: doi:10.14218/JCTH.2015.00007
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548351/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:22857075
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters