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dc.contributor.authorPetraro, Paul
dc.contributor.authorDuggan, Christopher Paul
dc.contributor.authorUrassa, Willy
dc.contributor.authorMsamanga, Gernard
dc.contributor.authorMakubi, Abel
dc.contributor.authorSpiegelman, Donna Lynn
dc.contributor.authorFawzi, Wafaie W.
dc.date.accessioned2016-02-22T20:26:50Z
dc.date.issued2013
dc.identifier.citationPetraro, P, C Duggan, W Urassa, G Msamanga, A Makubi, D Spiegelman, and W W Fawzi. 2013. “Determinants of Anemia in Postpartum HIV-Negative Women in Dar Es Salaam, Tanzania.” Eur J Clin Nutr 67 (7) (April 24): 708–717. doi:10.1038/ejcn.2013.71.en_US
dc.identifier.issn0954-3007en_US
dc.identifier.issn1476-5640en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:25499836
dc.description.abstractObjective: The determinants of anemia during both pregnancy and postpartum recovery remain incompletely understood in sub-Saharan African women. Subjects/methods: In a prospective cohort study among pregnant women, we assessed dietary, biochemical, anthropometric, infectious and sociodemographic factors at baseline. In multivariate Cox proportional hazards models, we examined predictors of incident anemia (hemoglobin <11 g/dl) and iron deficiency anemia (anemia plus mean corpuscular volume <80fL), and recovery from anemia and iron deficiency anemia through 18 months postpartum at antenatal clinics in Dar es Salaam, Tanzania between 2001 and 2005. A total of 2364 non-anemic pregnant women and 4884 anemic women were enrolled between 12 and 27 weeks of gestation. Results: In total, 292 women developed anemia during the postpartum period and 165 developed iron deficiency anemia, whereas 2982 recovered from baseline anemia and 2044 from iron deficiency anemia. Risk factors for postpartum anemia were delivery complications (RR 1.6, 95% confidence interval (CI) 1.13, 2.22) and low postpartum CD4 cell count (RR 1.73, 95% CI 0.96, 3.17). Iron/folate supplementation during pregnancy had a protective relationship with the incidence of iron deficiency anemia. Absence of delivery complications, education status and iron/folate supplementation were positively associated with time to recovery from iron deficiency. Conclusion: Maternal nutritional status during pregnancy, prenatal iron/folate supplementation, perinatal care, and prevention and management of infections, such as malaria, are modifiable risk factors for the occurrence of, and recovery from, anemia.en_US
dc.language.isoen_USen_US
dc.publisherNature Publishing Groupen_US
dc.relation.isversionofdoi:10.1038/ejcn.2013.71en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775569/en_US
dash.licenseLAA
dc.subjectanemiaen_US
dc.subjectpostpartumen_US
dc.subjectiron deficiencyen_US
dc.subjectpregnancyen_US
dc.titleDeterminants of Anemia in Postpartum HIV-Negative Women in Dar es Salaam, Tanzaniaen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalEuropean Journal of Clinical Nutritionen_US
dash.depositing.authorFawzi, Wafaie W.
dash.waiver2013-02-27
dc.date.available2016-02-22T20:26:50Z
dc.identifier.doi10.1038/ejcn.2013.71*
dash.contributor.affiliatedDuggan, Christopher
dash.contributor.affiliatedSpiegelman, Donna
dash.contributor.affiliatedFawzi, Wafaie
dc.identifier.orcid0000-0003-4006-4650
dc.identifier.orcid0000-0002-2908-600X


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