Validating the Children’s Depression Inventory in the context of Rwanda

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Validating the Children’s Depression Inventory in the context of Rwanda

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Title: Validating the Children’s Depression Inventory in the context of Rwanda
Author: Binagwaho, Agnes; Fawzi, Mary C. Smith; Agbonyitor, Mawuena; Nsanzimana, Sabin; Karema, Corine; Remera, Eric; Mutabazi, Vincent; Shyirambere, Cyprien; Cyamatare, Patrick; Nutt, Cameron; Wagner, Claire; Condo, Jeanine; Misago, Nancy; Kayiteshonga, Yvonne

Note: Order does not necessarily reflect citation order of authors.

Citation: Binagwaho, A., M. C. S. Fawzi, M. Agbonyitor, S. Nsanzimana, C. Karema, E. Remera, V. Mutabazi, et al. 2016. “Validating the Children’s Depression Inventory in the context of Rwanda.” BMC Pediatrics 16 (1): 29. doi:10.1186/s12887-016-0565-2. http://dx.doi.org/10.1186/s12887-016-0565-2.
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Abstract: Background: Depression is often co-morbid with chronic conditions, and when combined with HIV it can increase progression and reduce survival. A brief and accurate screening tool for depression among children living with HIV is necessary to increase access to mental health care and improve HIV-related outcomes in the long-term. Methods: A validation study was conducted, comparing the Children’s Depression Inventory (CDI) with a structured clinical assessment as the gold standard among children living with HIV ages 7-14 years in Rwanda. The response rate was 87 % and the analysis was performed among 100 study participants. Results: Twenty-five percent of children had a diagnosis of depression based on the clinical interview. Sensitivity of the CDI ranged from 44 to 76 % and specificity was 92 to 100 % for cut-off scores from 5 to 9. The area under the curve (AUC) for receiver operating characteristic analysis, an estimate of overall accuracy, was 0.87 (95 % confidence interval: 0.77 – 0.97). Conclusions: The significant prevalence of depression among children living with HIV in Rwanda reflects a critical need to advance mental health care in this population. Although overall accuracy of the CDI is reasonable in this context, further research needs to be done to develop a more sensitive measure of depression in this vulnerable population. Development of a highly sensitive screening measure will be a fundamental step towards improving access to mental health care among children living with HIV, potentially improving health outcomes and quality of life in the long-term as this vulnerable population transitions into adulthood.
Published Version: doi:10.1186/s12887-016-0565-2
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762156/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:25658376
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