LOng-term follow-up after liVE kidney donation (LOVE) study: a longitudinal comparison study protocol
Klop, Karel W. J.
Kimenai, Hendrikus J. A. N.
van de Wetering, Jacqueline
Massey, Emma K.
Ijzermans, Jan N. M.Note: Order does not necessarily reflect citation order of authors.
MetadataShow full item record
CitationJanki, S., K. W. J. Klop, H. J. A. N. Kimenai, J. van de Wetering, W. Weimar, E. K. Massey, A. Dehghan, et al. 2016. “LOng-term follow-up after liVE kidney donation (LOVE) study: a longitudinal comparison study protocol.” BMC Nephrology 17 (1): 14. doi:10.1186/s12882-016-0227-5. http://dx.doi.org/10.1186/s12882-016-0227-5.
AbstractBackground: The benefits of live donor kidney transplantation must be balanced against the potential harm to the donor. Well-designed prospective studies are needed to study the long-term consequences of kidney donation. Methods: The “LOng-term follow-up after liVE kidney donation” (LOVE) study is a single center longitudinal cohort study on long-term consequences after living kidney donation. We will study individuals who have donated a kidney from 1981 through 2010 in the Erasmus University Medical Center in Rotterdam, The Netherlands. In this time period, 1092 individuals donated a kidney and contact information is available for all individuals. Each participating donor will be matched (1:4) to non-donors derived from the population-based cohort studies of the Rotterdam Study and the Study of Health in Pomerania. Matching will be based on baseline age, gender, BMI, ethnicity, kidney function, blood pressure, pre-existing co-morbidity, smoking, the use of alcohol and highest education degree. Follow-up data is collected on kidney function, kidney-related comorbidity, mortality, quality of life and psychological outcomes in all participants. Discussion This study will provide evidence on the long-term consequences of live kidney donation for the donor compared to matched non-donors and evaluate the current donor eligibility criteria. Trial registration Dutch Trial Register NTR3795.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:25658474
- SPH Scholarly Articles