H1N1 vaccination and adults with underlying health conditions in the US

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H1N1 vaccination and adults with underlying health conditions in the US

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Title: H1N1 vaccination and adults with underlying health conditions in the US
Author: Goldstein, Edward; Lipsitch, Marc

Note: Order does not necessarily reflect citation order of authors.

Citation: Goldstein, Edward, and Marc Lipsitch. 2009. “H1N1 Vaccination and Adults with Underlying Health Conditions in the US.” PLoS Currents 1 (December 7): RRN1132. doi:10.1371/currents.rrn1132.
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Abstract: 65% of fatalities from pH1N1 infections in a large US case series occur in adults with underlying health conditions other than pregnancy, but it appears that only relatively few high-risk adults will get vaccinated during the fall wave of pH1N1 transmission. There are several reasons for this problem; the most important is vaccine shortage. High risk adults (other than pregnant women) were not part of the initial, narrow priority cohort which included pregnant women and children ages 0.5-4; this is despite the fact that some of those high risk groups, such as adults with immunosuppressive conditions and possibly individuals with neurological disorders, have a relative risk for fatality (per capita) higher than pregnant women, and over 28-fold higher than healthy children under the age of 4. With more vaccine becoming available than needed in the initial priority cohort, a broader group which includes high risk adults and individuals under 24 becomes eligible for vaccine in many locations. Nonetheless, due to continuing high demand, high-risk adults face competition for vaccine from healthy individuals under 24; additionally, some locations specifically prioritize school students over high-risk adults. Finally, there is an issue of awareness and a shortage of specific channels that target high risk adults other than pregnant women and facilitate vaccine distribution among them in the US.
Published Version: doi:10.1371/currents.RRN1132
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781303/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:25753233
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