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dc.contributor.authorGoldstein, Edward
dc.contributor.authorLipsitch, Marc
dc.date.accessioned2016-03-08T19:37:19Z
dc.date.issued2009
dc.identifierQuick submit: 2016-01-08T15:12:05-05:00
dc.identifier.citationGoldstein, Edward, and Marc Lipsitch. 2009. “H1N1 Vaccination and Adults with Underlying Health Conditions in the US.” PLoS Currents 1 (December 7): RRN1132. doi:10.1371/currents.rrn1132.en_US
dc.identifier.issn2157-3999en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:25753233
dc.description.abstract65% of fatalities from pH1N1 infections in a large US case series occur in adults with underlying health conditions other than pregnancy, but it appears that only relatively few high-risk adults will get vaccinated during the fall wave of pH1N1 transmission. There are several reasons for this problem; the most important is vaccine shortage. High risk adults (other than pregnant women) were not part of the initial, narrow priority cohort which included pregnant women and children ages 0.5-4; this is despite the fact that some of those high risk groups, such as adults with immunosuppressive conditions and possibly individuals with neurological disorders, have a relative risk for fatality (per capita) higher than pregnant women, and over 28-fold higher than healthy children under the age of 4. With more vaccine becoming available than needed in the initial priority cohort, a broader group which includes high risk adults and individuals under 24 becomes eligible for vaccine in many locations. Nonetheless, due to continuing high demand, high-risk adults face competition for vaccine from healthy individuals under 24; additionally, some locations specifically prioritize school students over high-risk adults. Finally, there is an issue of awareness and a shortage of specific channels that target high risk adults other than pregnant women and facilitate vaccine distribution among them in the US.en_US
dc.language.isoen_USen_US
dc.publisherPublic Library of Science (PLoS)en_US
dc.relation.isversionofdoi:10.1371/currents.RRN1132en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781303/en_US
dash.licenseLAA
dc.titleH1N1 vaccination and adults with underlying health conditions in the USen_US
dc.typeJournal Articleen_US
dc.date.updated2016-01-08T20:12:06Z
dc.description.versionVersion of Recorden_US
dc.rights.holderMarc Lipsitch
dc.relation.journalPLoS Curren_US
dash.depositing.authorLipsitch, Marc
dc.date.available2016-03-08T19:37:19Z
dash.funder.nameUS National Institutes of Health Models of Infectious Disease Agent Study Cooperative Agreementsen_US
dash.funder.nameHarvard Center for Communicable Disease Dynamicsen_US
dash.funder.award5U01GM076497en_US
dash.funder.award1U54GM088588en_US
dc.identifier.doi10.1371/currents.RRN1132*
dash.contributor.affiliatedGoldstein, Edward
dash.contributor.affiliatedLipsitch, Marc


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