Vitamin Status among Breastfed Infants in Bhaktapur, Nepal

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Vitamin Status among Breastfed Infants in Bhaktapur, Nepal

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Title: Vitamin Status among Breastfed Infants in Bhaktapur, Nepal
Author: Ulak, Manjeswori; Chandyo, Ram; Thorne-Lyman, Andrew Lucian; Henjum, Sigrun; Ueland, Per; Midttun, Øivind; Shrestha, Prakash; Fawzi, Wafaie W.; Graybill, Lauren Aiko; Strand, Tor

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Citation: Ulak, Manjeswori, Ram Chandyo, Andrew Thorne-Lyman, Sigrun Henjum, Per Ueland, Øivind Midttun, Prakash Shrestha, Wafaie Fawzi, Lauren Graybill, and Tor Strand. 2016. “Vitamin Status Among Breastfed Infants in Bhaktapur, Nepal.” Nutrients 8 (3) (March 8): 149. doi:10.3390/nu8030149.
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Abstract: Vitamin deficiencies are known to be common among infants residing in low- and middle-income countries but relatively few studies have assessed several biochemical parameters simultaneously. The objective of the study was to describe the status of vitamins (A, D, E, B₆, B12 and folate) in breastfed infants. We measured the plasma concentrations of trans retinol, 25 hydroxy vitamin D, α-tocopherol, pyridoxal 5'-phosphate, cobalamin, folate, methylmalonic acid, homocysteine, hemoglobin and C-reactive protein from 467 randomly selected infants. One in five (22%) was deficient in at least one vitamin. Mean (SD) plasma folate concentration was 73 (35) nmol/L, and no infant in the sample was folate deficient. Vitamin B₆ deficiency and vitamin B12 deficiency was found in 22% and 17% of the infants, respectively. Elevated plasma methylmalonic acid or total homocysteine concentration was found in 82% and 62% of infants, respectively. Fifteen percent of infants were vitamin A deficient and 65% were marginally deficient in vitamin A. Fewer than 5% of infants had low plasma vitamin D concentration or vitamin E concentration (α-tocopherol <9.3 µmol/L). Our results illustrate the importance of continued supplementation campaigns and support the expansion of food fortification and dietary diversification programs that target children and women in Nepal.
Published Version: doi:10.3390/nu8030149
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808878/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:26835961
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