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dc.contributor.authorMwiru, R. S.
dc.contributor.authorSpiegelman, Donna Lynn
dc.contributor.authorDuggan, Christopher Paul
dc.contributor.authorSeage, George R.
dc.contributor.authorSemu, H.
dc.contributor.authorChalamilla, G
dc.contributor.authorKisenge, R.
dc.contributor.authorFawzi, Wafaie W.
dc.date.accessioned2016-04-26T19:23:39Z
dc.date.issued2013
dc.identifier.citationMwiru, R. S., D. Spiegelman, C. Duggan, G. R. Seage, H. Semu, G. Chalamilla, R. Kisenge, and W. W. Fawzi. 2013. “Nutritional Status and Other Baseline Predictors of Mortality Among HIV-Infected Children Initiating Antiretroviral Therapy in Tanzania.” Journal of the International Association of Providers of AIDS Care (JIAPAC) 14 (2) (October 8): 172–179. doi:10.1177/2325957413500852.en_US
dc.identifier.issn2325-9574en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:26836020
dc.description.abstractBACKGROUND: We assembled a prospective cohort of 3144 children less than 15 years of age initiating antiretroviral therapy (ART) in Dar es Salaam, Tanzania. METHODS: The relationships of nutritional status and other baseline characteristics in relation to mortality were examined using Cox proportional hazards model. RESULTS: Compared with children with weight for age (WAZ) > -1, those with WAZ ≤ -2 to < -3 had a nearly double risk of death (relative risk [RR], 1.85; 95% confidence interval [CI], 1.10-3.11), and among those with WAZ ≤ -3, the risk more than tripled (RR, 3.36; 95% CI, 2.12-5.32). Other baseline risk factors for overall mortality included severe anemia (P < .001), severe immune suppression (P = .02), history of tuberculosis (P = .01), opportunistic infections (P < .001), living in the poorest district (P < .001), and advanced World Health Organization stage (P = .003). CONCLUSIONS: To sustain the obtained benefit of ART in this setting, interventions to improve nutritional status may be used as an adjunct to ART.en_US
dc.language.isoen_USen_US
dc.publisherSAGE Publicationsen_US
dc.relation.isversionofdoi:10.1177/2325957413500852en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627587/en_US
dash.licenseOAP
dc.subjectAIDSen_US
dc.subjectHIVen_US
dc.subjectTanzaniaen_US
dc.subjectchildrenen_US
dc.subjectmortalityen_US
dc.titleNutritional Status and Other Baseline Predictors of Mortality among HIV-Infected Children Initiating Antiretroviral Therapy in Tanzaniaen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalJournal of the International Association of Providers of AIDS Care (JIAPAC)en_US
dash.depositing.authorFawzi, Wafaie W.
dc.date.available2016-04-26T19:23:39Z
dc.identifier.doi10.1177/2325957413500852*
dash.contributor.affiliatedDuggan, Christopher
dash.contributor.affiliatedChalamilla, Guerino
dash.contributor.affiliatedFawzi, Wafaie
dash.contributor.affiliatedSeage, George
dash.contributor.affiliatedSpiegelman, Donna


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