How drug resistance takes shape
Citation
Jeselsohn, Rinath, and Myles Brown. 2016. “How drug resistance takes shape.” eLife 5 (1): e14973. doi:10.7554/eLife.14973. http://dx.doi.org/10.7554/eLife.14973.Abstract
Mutations in a hormone receptor can lead to therapeutic resistance by making it less able to bind and respond to hormone blocking drugs and by making it active, even when the hormome is not present.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821798/pdf/Terms of Use
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