dc.contributor.author | Trzcinski, K. | |
dc.contributor.author | Thompson, Claudette M. | |
dc.contributor.author | Malley, Richard | |
dc.contributor.author | Lipsitch, Marc | |
dc.date.accessioned | 2016-05-10T18:42:00Z | |
dc.date.issued | 2005 | |
dc.identifier.citation | Trzcinski, K., C. Thompson, R. Malley, and M. Lipsitch. 2005. “Antibodies to Conserved Pneumococcal Antigens Correlate with, but Are Not Required for, Protection Against Pneumococcal Colonization Induced by Prior Exposure in a Mouse Model.” Infection and Immunity 73 (10) (September 21): 7043–7046. doi:10.1128/iai.73.10.7043-7046.2005. | en_US |
dc.identifier.issn | 0019-9567 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:26978424 | |
dc.description.abstract | In mice following intranasal exposure to Streptococcus pneumoniae, protection against pneumococcal colonization was independent of antibody but dependent on CD4+ T cells. Nonetheless, concentrations of antibodies to three conserved pneumococcal antigens correlated with protection against colonization. Concentrations of antibodies to conserved pneumococcal antigens may be correlates of protection without being effectors of protection. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | American Society for Microbiology | en_US |
dc.relation.isversionof | doi:10.1128/IAI.73.10.7043-7046.2005 | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1230924/ | en_US |
dash.license | LAA | |
dc.title | Antibodies to Conserved Pneumococcal Antigens Correlate with, but Are Not Required for, Protection against Pneumococcal Colonization Induced by Prior Exposure in a Mouse Model | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Infection and Immunity | en_US |
dash.depositing.author | Lipsitch, Marc | |
dc.date.available | 2016-05-10T18:42:00Z | |
dash.funder.name | NIH | en_US |
dash.funder.award | 5 R01AI048935 | en_US |
dash.funder.award | K08 AI51526-01 | en_US |
dc.identifier.doi | 10.1128/IAI.73.10.7043-7046.2005 | * |
dash.contributor.affiliated | Thompson, Claudette | |
dash.contributor.affiliated | Malley, Richard | |
dash.contributor.affiliated | Lipsitch, Marc | |