Capsule Homology Does Not Increase the Frequency of Transformation of Linked Penicillin Binding Proteins PBP 1a and PBP 2x in Streptococcus pneumoniae

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Capsule Homology Does Not Increase the Frequency of Transformation of Linked Penicillin Binding Proteins PBP 1a and PBP 2x in Streptococcus pneumoniae

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Title: Capsule Homology Does Not Increase the Frequency of Transformation of Linked Penicillin Binding Proteins PBP 1a and PBP 2x in Streptococcus pneumoniae
Author: Trzcinski, K.; MacNeil, A.; Klugman, Keith; Lipsitch, Marc

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Citation: Trzcinski, K., A. MacNeil, K. P. Klugman, and M. Lipsitch. 2005. “Capsule Homology Does Not Increase the Frequency of Transformation of Linked Penicillin Binding Proteins PBP 1a and PBP 2x in Streptococcus Pneumoniae.” Antimicrobial Agents and Chemotherapy 49 (4) (March 25): 1591–1592. doi:10.1128/aac.49.4.1591-1592.2005.
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Abstract: Penicillin resistance is mainly confined to a limited number of Streptococcus pneumoniae serotypes. Given linkage between the capsular biosynthesis locus and two penicillin binding proteins, we tested whether capsule homology increases transformation rates of penicillin resistance. Transformation rates in homologous donor-recipient pairs were no higher than expected, falsifying this hypothesis.
Published Version: doi:10.1128/AAC.49.4.1591-1592.2005
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1068637/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:26978425
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