Dyslipidemia in an HIV-Positive Antiretroviral Treatment-Naive Population in Dar es Salaam, Tanzania
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CitationArmstrong, Catharina, Enju Liu, James Okuma, Donna Spiegelman, Chalamilla Guerino, Marina Njelekela, Steve Grinspoon, Wafaie Fawzi, and Claudia Hawkins. 2011. “Dyslipidemia in an HIV-Positive Antiretroviral Treatment-Naive Population in Dar Es Salaam, Tanzania.” JAIDS Journal of Acquired Immune Deficiency Syndromes 57 (2) (June): 141–145. doi:10.1097/qai.0b013e318219a3d1.
AbstractLimited data are available on dyslipidemia in HIV-infected patients in resource-limited settings (RLS). We performed a cross-sectional analysis in ART-naïve, non-fasting HIV-infected patients in Tanzania between November 2004-June 2008. Robust linear regression modeling was performed. Lipid parameters were assessed in 12,513 patients (65% women; median (IQR) age, 36 (30–42) years; CD4 count, 143 (51–290) cells/mm3). Low HDL was prevalent in 67% and increased TG in 28%. High triglyceride and low HDL levels were associated with low CD4 counts (P<0.001). In this ART-naïve Tanzanian population, dyslipidemia was highly prevalent and associated with advanced disease. The impact of ART on these changes requires further exploration.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:27001547
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