dc.contributor.author | Chen, Yiwen | |
dc.contributor.author | Meyer, Clifford | |
dc.contributor.author | Liu, Tao | |
dc.contributor.author | Li, Wei | |
dc.contributor.author | Liu, Jun | |
dc.contributor.author | Liu, Xiaole (Shirley) Shirley | |
dc.date.accessioned | 2016-05-13T18:37:37Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Chen, Yiwen, Clifford A Meyer, Tao Liu, Wei Li, Jun S Liu, and Xiaole Shirley Liu. 2011. “MM-ChIP Enables Integrative Analysis of Cross-Platform and Between-Laboratory ChIP-Chip or ChIP-Seq Data.” Genome Biology 12 (2): R11. doi:10.1186/gb-2011-12-2-r11. | en_US |
dc.identifier.issn | 1465-6906 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:27002573 | |
dc.description.abstract | The ChIP-chip and ChIP-seq techniques enable genome-wide mapping of in vivo protein-DNA interactions and chromatin states. The cross-platform and between-laboratory variation poses a challenge to the comparison and integration of results from different ChIP experiments. We describe a novel method, MM-ChIP, which integrates information from cross-platform and between-laboratory ChIP-chip or ChIP-seq datasets. It improves both the sensitivity and the specificity of detecting ChIP-enriched regions, and is a useful meta-analysis tool for driving discoveries from multiple data sources. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Springer Science + Business Media | en_US |
dc.relation.isversionof | doi:10.1186/gb-2011-12-2-r11 | en_US |
dash.license | LAA | |
dc.title | MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Genome Biol | en_US |
dash.depositing.author | Liu, Jun | |
dc.date.available | 2016-05-13T18:37:37Z | |
dc.identifier.doi | 10.1186/gb-2011-12-2-r11 | * |
dash.authorsordered | false | |
dash.contributor.affiliated | Chen, Yiwen | |
dash.contributor.affiliated | Meyer, Clifford | |
dash.contributor.affiliated | Liu, Tao | |
dash.contributor.affiliated | Liu, Xiaole | |
dash.contributor.affiliated | Liu, Jun | |