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dc.contributor.authorOlivares, Ana Mariaen_US
dc.contributor.authorMoreno-Ramos, Oscar Andrésen_US
dc.contributor.authorHaider, Neena B.en_US
dc.date.accessioned2016-06-14T18:51:43Z
dc.date.issued2015en_US
dc.identifier.citationOlivares, Ana Maria, Oscar Andrés Moreno-Ramos, and Neena B. Haider. 2015. “Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases.” Journal of Experimental Neuroscience 9 (Suppl 2): 93-121. doi:10.4137/JEN.S25480. http://dx.doi.org/10.4137/JEN.S25480.en
dc.identifier.issn1179-0695en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:27320246
dc.description.abstractThe nuclear hormone receptor (NHR) superfamily is composed of a wide range of receptors involved in a myriad of important biological processes, including development, growth, metabolism, and maintenance. Regulation of such wide variety of functions requires a complex system of gene regulation that includes interaction with transcription factors, chromatin-modifying complex, and the proper recognition of ligands. NHRs are able to coordinate the expression of genes in numerous pathways simultaneously. This review focuses on the role of nuclear receptors in the central nervous system and, in particular, their role in regulating the proper development and function of the brain and the eye. In addition, the review highlights the impact of mutations in NHRs on a spectrum of human diseases from autism to retinal degeneration.en
dc.language.isoen_USen
dc.publisherLibertas Academicaen
dc.relation.isversionofdoi:10.4137/JEN.S25480en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859451/pdf/en
dash.licenseLAAen_US
dc.subjectcentral nervous systemen
dc.subjectnuclear hormone receptorsen
dc.subjectregulationen
dc.subjectbrainen
dc.subjecteyeen
dc.subjecthuman diseaseen
dc.titleRole of Nuclear Receptors in Central Nervous System Development and Associated Diseasesen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalJournal of Experimental Neuroscienceen
dash.depositing.authorOlivares, Ana Mariaen_US
dc.date.available2016-06-14T18:51:43Z
dc.identifier.doi10.4137/JEN.S25480*
dash.contributor.affiliatedOlivares, Ana
dash.contributor.affiliatedHaider, Neena


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