Consumers report lower confidence in their genetics knowledge following direct-to-consumer personal genomic testing
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CitationCarere, Deanna Alexis, Peter Kraft, Kimberly A. Kaphingst, J. Scott Roberts, and Robert C. Green. 2015. “Consumers report lower confidence in their genetics knowledge following direct-to-consumer personal genomic testing.” Genetics in medicine : official journal of the American College of Medical Genetics 18 (1): 65-72. doi:10.1038/gim.2015.34. http://dx.doi.org/10.1038/gim.2015.34.
AbstractPurpose To measure changes to genetics knowledge and self-efficacy following personal genomic testing (PGT). Methods: New customers of 23andMe and Pathway Genomics completed a series of online surveys. Prior to receipt of results, and 6 months post-results, we measured genetics knowledge (9 true/false items) and genetics self-efficacy (5 Likert-scale items) and used paired methods to evaluate change over time. Correlates of change (e.g., decision regret) were identified using linear regression. Results: 998 PGT customers (59.9% female; 85.8% White; mean age 46.9±15.5 years) were included in our analyses. Mean genetics knowledge score out of 9 was 8.15±0.95 at baseline and 8.25±0.92 at 6 months (p = .0024). Mean self-efficacy score out of 35 was 29.06±5.59 at baseline and 27.7±5.46 at 6 months (p < .0001); on each item, 30–45% of participants reported lower self-efficacy following PGT. Change in self-efficacy was positively associated with health care provider consultation (p = .0042), impact of PGT on perceived control over one’s health (p < .0001), and perceived value of PGT (p < .0001), and negatively associated with decision regret (p < .0001). Conclusion: Lowered genetics self-efficacy following PGT may reflect an appropriate reevaluation by consumers in response to receiving complex genetic information.
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