Evolutionary features of thyroid cancer in patients with thyroidectomies from 2008 to 2013 in China

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Evolutionary features of thyroid cancer in patients with thyroidectomies from 2008 to 2013 in China

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Title: Evolutionary features of thyroid cancer in patients with thyroidectomies from 2008 to 2013 in China
Author: Liu, Xiaoyun; Zhu, Lijun; Wang, Zhixiao; Cui, Dai; Chen, Huanhuan; Duan, Yu; Shen, Meiping; Lu, Hui; Zhang, Zhihong; Chen, Jiawei; Alexander, Erik K.; Yang, Tao; Wang, Xiaodong

Note: Order does not necessarily reflect citation order of authors.

Citation: Liu, X., L. Zhu, Z. Wang, D. Cui, H. Chen, Y. Duan, M. Shen, et al. 2016. “Evolutionary features of thyroid cancer in patients with thyroidectomies from 2008 to 2013 in China.” Scientific Reports 6 (1): 28414. doi:10.1038/srep28414. http://dx.doi.org/10.1038/srep28414.
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Abstract: To evaluate the characteristics of thyroid carcinoma over time, we carried out a retrospective study to illustrate the evolutionary features of thyroid carcinoma. All records of thyroidectomies from the First Affiliated Hospital of Nanjing Medical University from 2008 to 2013 were obtained focusing on pathological diagnosis, size, local lymph node metastasis (LNM) of the tumors. The thyroid cancer detection rate increased from 24.6% to 41.5% significantly (P < 0.05). Papillary thyroid carcinoma (PTC) remained to be the most common type counting 86.4% of all thyroid carcinomas. In all 1,704 PTCs, microPTC (mPTC) with maximum diameter less than or equal to 10 mm has become the dominant form taking up 56.5% of all PTCs in 2013 while only 43.1% in 2008. The mean maximum tumor size has decreased from 17.8 mm to 12.2 mm significantly (P < 0.05). However, the average age, female dominance, and local LNM remained similarly in the past six years. Logistic regression test showed that the determinants for local LNM were age, gender and tumor size. mPTC has become the most common form of thyroid carcinoma detected during thyroidectomies in China while other features of thyroid carcinoma remained similarly in the recent years.
Published Version: doi:10.1038/srep28414
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916471/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:27662076
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