Pursuing Quality in the Application of Bladder Cancer Quality of Life Research

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Pursuing Quality in the Application of Bladder Cancer Quality of Life Research

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Title: Pursuing Quality in the Application of Bladder Cancer Quality of Life Research
Author: Mohamed, N.E.; Gilbert, F.; Lee, C.T.; Sfakianos, J.; Knauer, C.; Mehrazin, R.; Badr, H.; Wittmann, D.; Downs, T.; Berry, D.; Given, B.; Wiklund, P.; Steineck, G.

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Citation: Mohamed, N., F. Gilbert, C. Lee, J. Sfakianos, C. Knauer, R. Mehrazin, H. Badr, et al. 2016. “Pursuing Quality in the Application of Bladder Cancer Quality of Life Research.” Bladder Cancer 2 (2): 139-149. doi:10.3233/BLC-160051. http://dx.doi.org/10.3233/BLC-160051.
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Abstract: Patient-reported outcomes (PRO), including health-related quality of life (HRQOL) measures, represent important means for evaluating patients’ health outcomes and for guiding health care decisions made by patients, practitioners, investigators, and policy makers. In spite of the large number of studies examining HRQOL in patients with bladder cancer, very few review articles investigated this topic. Because these review studies report mixed results, incorporating bladder cancer HRQOL measures into standard urological practice is not a viable option. In this non-systematic review of the literature and commentary we note some general concerns regarding PRO research, but our primary focus is on the HRQOL methodology within the context of two types of bladder cancer: muscle invasive and non-muscle invasive bladder cancer. Considering bladder cancer HRQOL as the interaction of four areas of the assessment process (i.e., what model of HRQOL to choose, what instruments are available to fit the choice, how interpretation of the resulting data fits the model, and how to derive some utility from the chosen model) and the two types of disease (i.e., muscle invasive and non-muscle invasive) may move us toward a better understanding of bladder cancer HRQOL. Establishing a useful model of perceived general health or specific symptoms is the first and most important step in developing the responsive bladder cancer HRQOL measures necessitated by clinical settings.
Published Version: doi:10.3233/BLC-160051
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927895/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:27662106
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