Cautionary optimism: caffeine and Parkinson’s disease risk

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Cautionary optimism: caffeine and Parkinson’s disease risk

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Title: Cautionary optimism: caffeine and Parkinson’s disease risk
Author: Sokol, Leonard L.; Young, Michael J.; Espay, Alberto J.; Postuma, Ronald B.

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Citation: Sokol, Leonard L., Michael J. Young, Alberto J. Espay, and Ronald B. Postuma. 2016. “Cautionary optimism: caffeine and Parkinson’s disease risk.” Journal of Clinical Movement Disorders 3 (1): 7. doi:10.1186/s40734-016-0037-8. http://dx.doi.org/10.1186/s40734-016-0037-8.
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Abstract: Most Parkinson’s disease (PD) patients present without known family history and without a diagnosed prodromal phase, underscoring the difficulty of employing primary (neuroprevention) and secondary (neuroprotection) preventions. In cases of monogenic forms, however, potential gene-carrying family members of a proband could engage in neuroprevention, such as exercise or diet modifications, to attenuate the risk of, or delay, disease development. However, a historical lack of recognized disease-modifying interventions has limited clinicians’ ability to recommend reliable preventive measures in caring for at-risk populations. We briefly analyze the first retrospective study to examine caffeine consumption and PD risk in a LRRK2 R1628P cohort.
Published Version: doi:10.1186/s40734-016-0037-8
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893836/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:27662145
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