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dc.contributor.authorSilverstein, Allisonen_US
dc.contributor.authorSood, Rachitaen_US
dc.contributor.authorCostas-Chavarri, Ainhoaen_US
dc.date.accessioned2016-08-09T14:52:23Z
dc.date.issued2016en_US
dc.identifier.citationSilverstein, Allison, Rachita Sood, and Ainhoa Costas-Chavarri. 2016. “Breast Cancer in Africa: Limitations and Opportunities for Application of Genomic Medicine.” International Journal of Breast Cancer 2016 (1): 4792865. doi:10.1155/2016/4792865. http://dx.doi.org/10.1155/2016/4792865.en
dc.identifier.issn2090-3170en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:27822119
dc.description.abstractAs genomic medicine gains clinical applicability across a spectrum of diseases, insufficient application in low-income settings stands to increase health disparity. Breast cancer screening, diagnosis, and treatment have benefited greatly from genomic medicine in high-income settings. As breast cancer is a leading cause of both cancer incidence and mortality in Africa, attention and resources must be applied to research and clinical initiatives to integrate genomic medicine into breast cancer care. In terms of research, there is a paucity of investigations into genetic determinants of breast cancer specific to African populations, despite consensus in the literature that predisposition and susceptibility genes vary between populations. Therefore, we need targeted strengthening of existing research efforts and support of new initiatives. Results will improve clinical care through screening and diagnosis with genetic testing specific to breast cancer in African populations. Clinically, genomic medicine can provide information capable of improving resource allocation to the population which most stands to benefit from increased screening or tailored treatment modalities. In situations where mammography or chemotherapy options are limited, this information will allow for the greatest impact. Implementation of genomic medicine will face numerous systemic barriers but is essential to improve breast cancer outcomes and survival.en
dc.language.isoen_USen
dc.publisherHindawi Publishing Corporationen
dc.relation.isversionofdoi:10.1155/2016/4792865en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927988/pdf/en
dash.licenseLAAen_US
dc.titleBreast Cancer in Africa: Limitations and Opportunities for Application of Genomic Medicineen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalInternational Journal of Breast Canceren
dash.depositing.authorSilverstein, Allisonen_US
dc.date.available2016-08-09T14:52:23Z
dc.identifier.doi10.1155/2016/4792865*
dash.contributor.affiliatedSood, Rachita
dash.contributor.affiliatedSilverstein, Allison
dash.contributor.affiliatedCostas-Chavarri, Ainhoa


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