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dc.contributor.authorMenon, Sonia S.en_US
dc.contributor.authorRossi, Rodolfoen_US
dc.contributor.authorNshimyumukiza, Leonen_US
dc.contributor.authorZinszer, Kateen_US
dc.date.accessioned2016-08-09T14:53:16Z
dc.date.issued2016en_US
dc.identifier.citationMenon, Sonia S., Rodolfo Rossi, Leon Nshimyumukiza, and Kate Zinszer. 2016. “Decentralized control of human visceral leishmaniasis in endemic urban areas of Brazil: a literature review.” Tropical Medicine and Health 44 (1): 9. doi:10.1186/s41182-016-0011-z. http://dx.doi.org/10.1186/s41182-016-0011-z.en
dc.identifier.issn1348-8945en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:27822276
dc.description.abstractObjectives: Human migration and concomitant HIV infections are likely to bring about major changes in the epidemiology of some parasitic infections in Brazil. Human visceral leishmaniasis (HVL) control is particularly fraught with intricacies. It is against a backdrop of decentralized health care that the complex HVL control initiatives are brought to bear. This comprehensive review aims to explore the obstacles facing decentralized HVL control in urban endemic areas in Brazil. Method A literature search was carried out in December 2015 by means of three databases: MEDLINE, Google Scholar, and Web of Science. Results: Although there have been many strides that have been made in elucidating the eco-epidemiology of Leishmania infantum, which forms the underpinnings of the national control program, transmission risk factors for HVL are still insufficiently elucidated in urban settings. Decentralized HVL epidemiological surveillance and control for animal reservoirs and vectors may compromise sustainability. In addition, it may hamper timely human HVL case management. With the burgeoning of the HIV-HVL co-infection, the potential human transmission may be underestimated. Conclusion: HVL is a disease with focal transmission at a critical juncture, which warrants that the bottlenecks facing the control program within contexts of decentralized healthcare systems be taken into account. In addition, HIV-driven HVL epidemics may substantially increase the transmission potential of the human reservoir. Calculating the basic reproductive number to fine-tune interventions will have to take into consideration the specific socio-economic development context.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/s41182-016-0011-zen
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940922/pdf/en
dash.licenseLAAen_US
dc.subjectHuman visceral leishmaniasisen
dc.subjectHIVen
dc.subjectControl and preventionen
dc.subjectDecentralizationen
dc.subjectHuman reservoiren
dc.subjectBasic reproductive numberen
dc.subjectVisceral leishmaniasisen
dc.subjectHIV co-infectionen
dc.titleDecentralized control of human visceral leishmaniasis in endemic urban areas of Brazil: a literature reviewen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalTropical Medicine and Healthen
dc.date.available2016-08-09T14:53:16Z
dc.identifier.doi10.1186/s41182-016-0011-z*


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