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dc.contributor.authorWang, Andrew Z
dc.contributor.authorGu, Frank
dc.contributor.authorZhang, Liangfang
dc.contributor.authorChan, Juliana M
dc.contributor.authorRadovic-Moreno, Aleksander
dc.contributor.authorShaikh, Mariam R
dc.contributor.authorFarokhzad, Omid Cameron
dc.date.accessioned2016-11-02T20:41:54Z
dc.date.issued2008
dc.identifier.citationWang, Andrew Z, Frank Gu, Liangfang Zhang, Juliana M Chan, Aleksander Radovic-Moreno, Mariam R Shaikh, and Omid C Farokhzad. 2008. Biofunctionalized Targeted Nanoparticles for Therapeutic Applications. Expert Opinion on Biological Therapy 8 (8) (July 9): 1063–1070. doi:10.1517/14712598.8.8.1063.en_US
dc.identifier.issn1471-2598en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:29293171
dc.description.abstractBackground: The development of nanoparticles for the delivery of therapeutic agents has introduced new opportunities for improvement in medical treatment. Recent efforts have focused on developing targeted nanoparticles for therapeutic delivery by functionalizing nanoparticle surfaces with targeting molecules, such as antibodies, peptides, small molecules and oligonucleotides. Objectives: This paper will review the state of targeted nanoparticles development. Methods: We will discuss nanoparticle platforms for therapeutic delivery, targeting molecules and the biofunctionalized targeted nanoparticles currently in development. Results/Conclusions: Biofunctionalized targeted nanoparticles have demonstrated exciting data in preclinical studies. With continued improvements, they may fulfill their potential as therapeutics carriers that can truly treat target tissue without affecting normal cells.en_US
dc.language.isoen_USen_US
dc.publisherInforma Healthcareen_US
dc.relation.isversionofdoi:10.1517/14712598.8.8.1063en_US
dc.relation.hasversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515649/en_US
dash.licenseLAA
dc.subjectBiofunctionalizeden_US
dc.subjectNanoparticleen_US
dc.subjectTargetingen_US
dc.subjectTargeted nanoparticlesen_US
dc.subjectTherapeutics deliveryen_US
dc.titleBiofunctionalized targeted nanoparticles for therapeutic applicationsen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalExpert Opinion on Biological Therapyen_US
dash.depositing.authorFarokhzad, Omid Cameron
dc.date.available2016-11-02T20:41:54Z
dc.identifier.doi10.1517/14712598.8.8.1063*
dash.contributor.affiliatedFarokhzad, Omid


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