Show simple item record

dc.contributor.authorFarivar, Rezaen_US
dc.contributor.authorGrigorov, Filipen_US
dc.contributor.authorvan der Kouwe, Andre J.en_US
dc.contributor.authorWald, Lawrence L.en_US
dc.contributor.authorKeil, Borisen_US
dc.date.accessioned2016-11-18T20:06:10Z
dc.date.issued2015en_US
dc.identifier.citationFarivar, Reza, Filip Grigorov, Andre J. van der Kouwe, Lawrence L. Wald, and Boris Keil. 2015. “Dense, shape‐optimized posterior 32‐channel coil for submillimeter functional imaging of visual cortex at 3T.” Magnetic Resonance in Medicine 76 (1): 321-328. doi:10.1002/mrm.25815. http://dx.doi.org/10.1002/mrm.25815.en
dc.identifier.issn0740-3194en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:29407763
dc.description.abstractPurpose Functional neuroimaging of small cortical patches such as columns is essential for testing computational models of vision, but imaging from cortical columns at conventional 3T fields is exceedingly difficult. By targeting the visual cortex exclusively, we tested whether combined optimization of shape, coil placement, and electronics would yield the necessary gains in signal‐to‐noise ratio (SNR) for submillimeter visual cortex functional MRI (fMRI). Method We optimized the shape of the housing to a population‐averaged atlas. The shape was comfortable without cushions and resulted in the maximally proximal placement of the coil elements. By using small wire loops with the least number of solder joints, we were able to maximize the Q factor of the individual elements. Finally, by planning the placement of the coils using the brain atlas, we were able to target the arrangement of the coil elements to the extent of the visual cortex. Results: The combined optimizations led to as much as two‐fold SNR gain compared with a whole‐head 32‐channel coil. This gain was reflected in temporal SNR as well and enabled fMRI mapping at 0.75 mm resolutions using a conventional GRAPPA‐accelerated gradient echo echo planar imaging. Conclusion: Integrated optimization of shape, electronics, and element placement can lead to large gains in SNR and empower submillimeter fMRI at 3T. Magn Reson Med 76:321–328, 2016. © 2015 Wiley Periodicals, Inc.en
dc.language.isoen_USen
dc.publisherJohn Wiley and Sons Inc.en
dc.relation.isversionofdoi:10.1002/mrm.25815en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747861/pdf/en
dash.licenseLAAen_US
dc.subjectFull Paperen
dc.subjectmagnetic resonance imagingen
dc.subjectphased‐arrayen
dc.subjectfMRIen
dc.subjectparallel imagingen
dc.subjectshape optimizationen
dc.subjectocular dominance columnsen
dc.subjectfunctional MRIen
dc.subjectorientation columnsen
dc.subjectaccelerated EPIen
dc.titleDense, shape‐optimized posterior 32‐channel coil for submillimeter functional imaging of visual cortex at 3Ten
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalMagnetic Resonance in Medicineen
dash.depositing.authorvan der Kouwe, Andre J.en_US
dc.date.available2016-11-18T20:06:10Z
dc.identifier.doi10.1002/mrm.25815*
dash.contributor.affiliatedKeil, Boris
dash.contributor.affiliatedVan Der Kouwe, Andre
dash.contributor.affiliatedWald, Lawrence


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record