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dc.contributor.authorTheis, Kevin R.en_US
dc.contributor.authorDheilly, Nolwenn M.en_US
dc.contributor.authorKlassen, Jonathan L.en_US
dc.contributor.authorBrucker, Robert M.en_US
dc.contributor.authorBaines, John F.en_US
dc.contributor.authorBosch, Thomas C. G.en_US
dc.contributor.authorCryan, John F.en_US
dc.contributor.authorGilbert, Scott F.en_US
dc.contributor.authorGoodnight, Charles J.en_US
dc.contributor.authorLloyd, Elisabeth A.en_US
dc.contributor.authorSapp, Janen_US
dc.contributor.authorVandenkoornhuyse, Philippeen_US
dc.contributor.authorZilber-Rosenberg, Ilanaen_US
dc.contributor.authorRosenberg, Eugeneen_US
dc.contributor.authorBordenstein, Seth R.en_US
dc.date.accessioned2016-12-02T15:25:57Z
dc.date.issued2016en_US
dc.identifier.citationTheis, K. R., N. M. Dheilly, J. L. Klassen, R. M. Brucker, J. F. Baines, T. C. G. Bosch, J. F. Cryan, et al. 2016. “Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes.” mSystems 1 (2): e00028-16. doi:10.1128/mSystems.00028-16. http://dx.doi.org/10.1128/mSystems.00028-16.en
dc.identifier.issn2379-5077en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:29626188
dc.description.abstractABSTRACT Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or limited to a certain spectrum of symbiotic interactions such as host-microbial coevolution? Critical discourse is necessary in this nascent area, but productive discourse requires that skeptics and proponents use the same lexicon. For instance, critiquing the hologenome concept is not synonymous with critiquing coevolution, and arguing that an entity is not a primary unit of selection dismisses the fact that the hologenome concept has always embraced multilevel selection. Holobionts and hologenomes are incontrovertible, multipartite entities that result from ecological, evolutionary, and genetic processes at various levels. They are not restricted to one special process but constitute a wider vocabulary and framework for host biology in light of the microbiome.en
dc.language.isoen_USen
dc.publisherAmerican Society for Microbiologyen
dc.relation.isversionofdoi:10.1128/mSystems.00028-16en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069740/pdf/en
dash.licenseLAAen_US
dc.subjectHost-Microbe Biologyen
dc.subjectEditor's Picken
dc.subjectecologyen
dc.subjectevolutionen
dc.subjecthologenomeen
dc.subjectmicrobiomeen
dc.titleGetting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomesen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalmSystemsen
dash.depositing.authorBrucker, Robert M.en_US
dc.date.available2016-12-02T15:25:57Z
dc.identifier.doi10.1128/mSystems.00028-16*
dash.authorsorderedfalse
dash.contributor.affiliatedBrucker, Robert


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