Characterization of Nucleic Acids by Nanopore Analysis
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Deamer, David W.
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CitationDeamer, David W. and Daniel Branton. 2002. Characterization of nucleic acids by nanopore analysis. Accounts of Chemical Research 35(10): 817-825.
AbstractSingle-stranded DNA and RNA molecules in solution can be driven through a nanoscopic pore by an applied electric field. As each molecule occupies the pore, a characteristic blockade of ionic current is produced. Information about length, composition, structure, and dynamic motion of the molecule can be deduced from modulations of the current blockade.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:3137806
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