Rectal mucosal dysplasia in Crohn's disease.

DSpace/Manakin Repository

Rectal mucosal dysplasia in Crohn's disease.

Citable link to this page

 

 
Title: Rectal mucosal dysplasia in Crohn's disease.
Author: Korelitz, B I; Lauwers, Gregory Y.; Sommers, S C

Note: Order does not necessarily reflect citation order of authors.

Citation: Korelitz, B I, G Y Lauwers, and S C Sommers. 1990. “Rectal Mucosal Dysplasia in Crohn’s Disease.” Gut 31 (12) (December 1): 1382–1386. doi:10.1136/gut.31.12.1382. http://dx.doi.org/10.1136/gut.31.12.1382.
Access Status: Full text of the requested work is not available in DASH at this time (“dark deposit”). For more information on dark deposits, see our FAQ.
Full Text & Related Files:
Abstract: Serial sections of 812 rectal biopsy specimens from 356 Crohn's disease patients were analysed for mucosal epithelial dysplasia. Dysplasia was found in 18 patients (5%), with four showing dysplasia on repeat biopsy specimen. In these 22 biopsy specimens the dysplasia was mild in 13, moderate in nine, and severe in none. Subsequently, three patients (17%) developed neoplasms including carcinoma in two and an adenomatous polyp in one. In colectomy specimens which showed dysplasia, significantly more dysplastic changes were found in seven patients who underwent colonic resection than in 10 others who underwent operation but had no prior dysplasia (p less than 0.001). Thirteen patients still have their rectum in situ and remain at risk of developing colonic cancer. Four carcinomas developed in patients with Crohn's disease who did not have dysplasia on rectal biopsy specimen.
Published Version: doi:10.1136/gut.31.12.1382
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:32513548
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters