Postural compensation strategy depends on the severity of vestibular damage
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https://doi.org/10.1016/j.heliyon.2017.e00270Metadata
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Thompson, Lara A., Csilla Haburcakova, and Richard F. Lewis. 2017. “Postural compensation strategy depends on the severity of vestibular damage.” Heliyon 3 (3): e00270. doi:10.1016/j.heliyon.2017.e00270. http://dx.doi.org/10.1016/j.heliyon.2017.e00270.Abstract
The purpose of this study was to investigate the effects of various levels of vestibular function on balance in two, free-standing rhesus monkeys. We hypothesized that postural control strategy depended on the severity of vestibular damage. More specifically, that increased muscle stiffness (via short-latency mechanisms) was adequate to compensate for mild damage, but long-latency mechanisms must be utilized for more severe vestibular damage. One animal was studied for pre-ablated and mild vestibular dysfunction states, while a second animal was studied in a pre-ablated and severe vestibular dysfunction state. The vestibulo-ocular reflex (VOR), an eye movement reflex directly linked to vestibular function, was used to quantify the level of vestibular damage. A postural feedback controller model, previously only used for human studies, was modified to interpret non-human primate postural responses (differences observed in the measured trunk roll) for these three levels of vestibular function. By implementing a feedback controller model, we were able to further interpret our empirical findings and model results were consistent with our above hypothesis. This study establishes a baseline for future studies of non-human primate posture.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367863/pdf/Terms of Use
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http://nrs.harvard.edu/urn-3:HUL.InstRepos:32630459
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