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dc.contributor.authorMereu, Elisabettaen_US
dc.contributor.authorPellegrino, Elisaen_US
dc.contributor.authorScarfò, Ireneen_US
dc.contributor.authorInghirami, Giorgioen_US
dc.contributor.authorPiva, Robertoen_US
dc.date.accessioned2017-05-01T19:27:04Z
dc.date.issued2017en_US
dc.identifier.citationMereu, Elisabetta, Elisa Pellegrino, Irene Scarfò, Giorgio Inghirami, and Roberto Piva. 2017. “The heterogeneous landscape of ALK negative ALCL.” Oncotarget 8 (11): 18525-18536. doi:10.18632/oncotarget.14503. http://dx.doi.org/10.18632/oncotarget.14503.en
dc.identifier.issnen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:32630507
dc.description.abstractAnaplastic Large Cell Lymphoma (ALCL) is a clinical and biological heterogeneous disease including systemic ALK positive and ALK negative entities. Whereas ALK positive ALCLs are molecularly characterized and readily diagnosed, specific immunophenotypic or genetic features to define ALK negative ALCL are missing, and their distinction from other T-cell non-Hodgkin lymphomas (T-NHLs) can be controversial. In recent years, great advances have been made in dissecting the heterogeneity of ALK negative ALCLs and in providing new diagnostic and treatment options for these patients. A new revision of the World Health Organization (WHO) classification promoted ALK negative ALCL to a definite entity that includes cytogenetic subsets with prognostic implications. However, a further understanding of the genetic landscape of ALK negative ALCL is required to dictate more effective therapeutic strategies specifically tailored for each subgroup of patients.en
dc.language.isoen_USen
dc.publisherImpact Journals LLCen
dc.relation.isversionofdoi:10.18632/oncotarget.14503en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392347/pdf/en
dash.licenseLAAen_US
dc.subjectanaplasticl large cell lymphomaen
dc.subjectmolecular classificationen
dc.subjecttherapyen
dc.subjectALK negativeen
dc.titleThe heterogeneous landscape of ALK negative ALCLen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalOncotargeten
dash.depositing.authorScarfò, Ireneen_US
dc.date.available2017-05-01T19:27:04Z
dc.identifier.doi10.18632/oncotarget.14503*
dash.contributor.affiliatedScarfo, Irene


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