Caregiver’s quality of life and its positive impact on symptomatology and quality of life of patients with schizophrenia

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Caregiver’s quality of life and its positive impact on symptomatology and quality of life of patients with schizophrenia

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Title: Caregiver’s quality of life and its positive impact on symptomatology and quality of life of patients with schizophrenia
Author: Caqueo-Urízar, Alejandra; Alessandrini, Marine; Urzúa, Alfonso; Zendjidjian, Xavier; Boyer, Laurent; Williams, David R.

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Citation: Caqueo-Urízar, Alejandra, Marine Alessandrini, Alfonso Urzúa, Xavier Zendjidjian, Laurent Boyer, and David R. Williams. 2017. “Caregiver’s quality of life and its positive impact on symptomatology and quality of life of patients with schizophrenia.” Health and Quality of Life Outcomes 15 (1): 76. doi:10.1186/s12955-017-0652-6. http://dx.doi.org/10.1186/s12955-017-0652-6.
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Abstract: Background: Although the quality of life (QoL) experienced by patients with schizophrenia has been recognized, few studies have assessed the relationship between the caregivers’ QoL and patients’ QoL. Methods: The study included 253 stabilized outpatients with schizophrenia and their caregivers from 3 Mental Health Services in Bolivia (N = 83), Chile (N = 85) and Peru (N = 85). Caregivers’ and patients’ QoL were respectively assessed using two specific QoL questionnaires (S-CGQoL and S-QoL 18). We collected socio-demographic information and clinical data. Multiple linear regressions were performed to determine which variables were associated with patient’s QoL. We tested the following hypothesis using structural equation modeling (SEM): caregivers’ QoL may have an indirect effect on patients’ QoL mediated by their influence of the severity of psychotic symptoms. Results: In the multivariate analysis, the caregivers’ QoL was not significantly associated with the patients’ QoL, except for one QoL dimension about relationship with family (Beta = 0.23). Among patients’ characteristics, being a woman and Aymara, having lower educational level, unemployment and severity of symptoms was significantly associated to a lower QoL. The SEM revealed a moderate significant association between caregivers’ QoL and psychotic symptoms severity (path coefficient = −0.32) and a significant association between psychotic symptoms severity and patients QoL (path coefficient = −0.40). The indirect effect of caregivers’ QoL on patients’ QoL was significant (mediated effect coefficient = 0.13). Conclusion: Improvement of caregiver’s QoL may have a direct impact on the psychotic symptoms of patients and indirectly on patient’s QoL, confirming the need for ongoing family interventions in these regions.
Published Version: doi:10.1186/s12955-017-0652-6
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395968/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:32630699
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