# Probing surface charge fluctuations with solid-state nanopores

 Title: Probing surface charge fluctuations with solid-state nanopores Author: Golovchenko, Jene; Garaj, Slaven; Hoogerheide, David Paul Note: Order does not necessarily reflect citation order of authors. Citation: Hoogerheide, David P., Slaven Garaj, and Jene A. Golovchenko. 2009. Probing surface charge fluctuations with solid-state nanopores. Physical Review Letters 102(25): 256804. Full Text & Related Files: 1249409471-PublishedArticle.pdf (387.5Kb; PDF) Abstract: We identify a contribution to the ionic current noise spectrum in solid-state nanopores that exceeds all other noise sources in the frequency band 0.1-10 kHz. Experimental studies of the dependence of this excess noise on pH and electrolyte concentration indicate that the noise arises from surface charge fluctuations. A quantitative model based on surface functional group protonization predicts the observed behaviors and allows us to locally measure protonization reaction rates. This noise can be minimized by operating the nanopore at a deliberately chosen pH. Published Version: 10.1103/PhysRevLett.102.256804 Other Sources: http://osc.hul.harvard.edu/Apps/app.php?app=forward&url=retrieve-upload.php%3Ffile%3D1249409471-PublishedArticle.pdf Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:3293523 Downloads of this work: