Odor Representations in Olfactory Cortex: Distributed Rate Coding and Decorrelated Population Activity
View/ Open
716683.pdf (1008.Kb)
Access Status
Full text of the requested work is not available in DASH at this time ("restricted access"). For more information on restricted deposits, see our FAQ.Published Version
https://doi.org/10.1016/j.neuron.2012.04.021Metadata
Show full item recordCitation
Miura, Keiji, Zachary F. Mainen, and Naoshige Uchida. 2012. Odor Representations in Olfactory Cortex: Distributed Rate Coding and Decorrelated Population Activity. Neuron 74, no. 6: 1087–1098.Abstract
How information encoded in neuronal spike trains is used to guide sensory decisions is a fundamental question. In olfaction, a single sniff is sufficient for fine odor discrimination but the neural representations on which olfactory decisions are based are unclear. Here, we recorded neural ensemble activity in the anterior piriformcortex (aPC) of rats performing an odor mixture categorization task. We show that odors evoke transient bursts locked to sniff onset and that odor identity can be better decoded using burst spike counts than by spike latencies or temporal patterns. Surprisingly, aPC ensembles also exhibited near-zero noise correlations during odor stimulation. Consequently, fewer than 100 aPC neurons provided sufficient information to account for behavioral speed and accuracy, suggesting that behavioral performance limits arise downstream of aPC. These findings demonstrate profound transformations in the dynamics of odor representations from the olfactory bulb to cortex and reveal likely substrates for odor-guided decisions.Other Sources
http://brainmind.umin.jp/PDF/wt13/2012Neuron.pdfCitable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:32969843
Collections
- FAS Scholarly Articles [17813]
Contact administrator regarding this item (to report mistakes or request changes)
Comments made during the workflow steps
FAR 2013 Uchida emailed 2016-04-20 MM Uchida emailed 2017-02-18 MM meta.dark