Diet and exercise changes following direct-to-consumer personal genomic testing

DSpace/Manakin Repository

Diet and exercise changes following direct-to-consumer personal genomic testing

Citable link to this page

 

 
Title: Diet and exercise changes following direct-to-consumer personal genomic testing
Author: Nielsen, Daiva Elena; Carere, Deanna Alexis; Wang, Catharine; Roberts, J. Scott; Green, Robert C.; Krier, Joel B.; Kalia, Sarah S.; Christensen, Kurt D.; Nielsen, Daiva E.; Lehmann, Lisa S.; Kraft, Peter; Ruffin, Mack T.; Le, Lan Q.; Ostergren, Jenny; Uhlmann, Wendy R.; Couper, Mick P.; Mountain, Joanna L.; Kiefer, Amy K.; Braunstein, Glenn; Crawford, Scott D.; Cupples, L. Adrienne; Chen, Clara A.; Gray, Stacy W.; Koenig, Barbara A.; Kaphingst, Kimberly; Gollust, Sarah

Note: Order does not necessarily reflect citation order of authors.

Citation: Nielsen, D. E., D. A. Carere, C. Wang, J. S. Roberts, R. C. Green, J. B. Krier, S. S. Kalia, et al. 2017. “Diet and exercise changes following direct-to-consumer personal genomic testing.” BMC Medical Genomics 10 (1): 24. doi:10.1186/s12920-017-0258-1. http://dx.doi.org/10.1186/s12920-017-0258-1.
Full Text & Related Files:
Abstract: Background: The impacts of direct-to-consumer personal genomic testing (PGT) on health behaviors such as diet and exercise are poorly understood. Our investigation aimed to evaluate diet and exercise changes following PGT and to determine if changes were associated with genetic test results obtained from PGT. Methods: Customers of 23andMe and Pathway Genomics completed a web-based survey prior to receiving PGT results (baseline) and 6 months post-results. Fruit and vegetable intake (servings/day), and light, vigorous and strength exercise frequency (days/week) were assessed. Changes in diet and exercise were examined using paired t-tests and linear regressions. Additional analyses examined whether outcomes differed by baseline self-reported health (SRH) or content of PGT results. Results: Longitudinal data were available for 1,002 participants. Significant increases were observed for vegetable intake (mean Δ = 0.11 (95% CI = 0.05, 0.17), p = 0.0003) and strength exercise (Δ = 0.14 (0.03, 0.25), p = 0.0153). When stratified by SRH, significant increases were observed for all outcomes among lower SRH participants: fruit intake, Δ = 0.11 (0.02, 0.21), p = 0.0148; vegetable intake, Δ = 0.16 (0.07, 0.25), p = 0.0005; light exercise, Δ = 0.25 (0.03, 0.47), p = 0.0263; vigorous exercise, Δ = 0.23 (0.06, 0.41), p = 0.0097; strength exercise, Δ = 0.19 (0.01, 0.37), p = 0.0369. A significant change among higher SRH participants was only observed for light exercise, and in the opposite direction: Δ = -0.2468 (-0.06, -0.44), p = 0.0111. Genetic results were not consistently associated with any diet or exercise changes. Conclusions: The experience of PGT was associated with modest, mostly positive changes in diet and exercise. Associations were independent of genetic results from PGT.
Published Version: doi:10.1186/s12920-017-0258-1
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412058/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33029792
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters