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dc.contributor.authorPortincasa, Pieroen_US
dc.contributor.authorBonfrate, Leonildeen_US
dc.contributor.authorde Bari, Ornellaen_US
dc.contributor.authorLembo, Anthonyen_US
dc.contributor.authorBallou, Sarahen_US
dc.date.accessioned2017-06-15T18:29:32Z
dc.date.issued2017en_US
dc.identifier.citationPortincasa, Piero, Leonilde Bonfrate, Ornella de Bari, Anthony Lembo, and Sarah Ballou. 2017. “Irritable bowel syndrome and diet.” Gastroenterology Report 5 (1): 11-19. doi:10.1093/gastro/gow047. http://dx.doi.org/10.1093/gastro/gow047.en
dc.identifier.issnen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:33029803
dc.description.abstractIrritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal tract and is one of the most commonly diagnosed gastrointestinal diseases. The impact of IBS on the general population is large due to its high prevalence, suboptimal medical treatments and significant economic burden. The pathophysiology of IBS is complex and treatments are often symptom-specific. The most common therapeutic approaches for IBS include education and reassurance, lifestyles (especially nutrition-based interventions), peripherally acting medications (which typically target motility), centrally acting medications (which target visceral hypersensitivity and pain) and psychological interventions (which aim to reduce the effects of stress or symptom-specific anxiety). A beneficial dietary approach might include the following measures: a diet low in fermentable oligo-,di- and monosaccharides and polyols (FODMAPs), limitation or exclusion of gas-producing foods and/or lactose and gluten and fiber supplementation in selected cases. New therapeutic agents, namely nutraceutics, are also an interesting option in the management of IBS patients. This paper will focus on available dietary interventions for IBS and will review the evidence for nutrition-based therapies.en
dc.language.isoen_USen
dc.publisherOxford University Pressen
dc.relation.isversionofdoi:10.1093/gastro/gow047en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444258/pdf/en
dash.licenseLAAen_US
dc.subjectirritable bowel syndromeen
dc.subjectfunctional gastrointestinal disordersen
dc.subjectfooden
dc.subjectFODMAPsen
dc.subjectintoleranceen
dc.subjectintestinal microbiotaen
dc.titleIrritable bowel syndrome and dieten
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalGastroenterology Reporten
dash.depositing.authorLembo, Anthonyen_US
dc.date.available2017-06-15T18:29:32Z
dc.identifier.doi10.1093/gastro/gow047*
dash.contributor.affiliatedBallou, Sarah
dash.contributor.affiliatedLembo, Anthony


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