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dc.contributor.authorDaley, George Quentin
dc.contributor.authorLensch, Mathew William
dc.contributor.authorJaenisch, Rudolf
dc.contributor.authorMeissner, Alexander
dc.contributor.authorPlath, Kathrin
dc.contributor.authorYamanaka, Shinya
dc.date.accessioned2017-07-20T20:49:55Z
dc.date.issued2009
dc.identifier.citationDaley, George Q., M. William Lensch, Rudolf Jaenisch, Alex Meissner, Kathrin Plath, and Shinya Yamanaka. 2009. “Broader Implications of Defining Standards for the Pluripotency of iPSCs.” Cell Stem Cell 4 (3) (March): 200–201. doi:10.1016/j.stem.2009.02.009.en_US
dc.identifier.issn1934-5909en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:33471099
dc.description.abstractWe read with great interest the excellent review by Maherali and Hochedlinger (2008) that recommends standards for characterization of pluripotent stem cell lines, especially the many new lines being generated using factor-based reprogramming techniques (induced pluripotent stem cells, or iPSCs). Of note was the suggestion that iPSCs should be assessed for “functional differentiation through the highest-stringency test acceptable.” For murine iPSCs, this means germline transmission following blastocyst chimerism, and for human iPSCs this means assessment of teratoma pathology.en_US
dc.language.isoen_USen_US
dc.publisherElsevier BVen_US
dc.relation.isversionofdoi:10.1016/j.stem.2009.02.009en_US
dash.licenseMETA_ONLY
dc.titleBroader Implications of Defining Standards for the Pluripotency of iPSCsen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalCell Stem Cellen_US
dash.depositing.authorMeissner, Alexander
dash.embargo.until10000-01-01
dc.identifier.doi10.1016/j.stem.2009.02.009*
workflow.legacycommentsMeissner emailed 2017-03-02 MM meta.darken_US
dash.contributor.affiliatedLensch, Willy
dash.contributor.affiliatedMeissner, Alexander
dash.contributor.affiliatedDaley, George


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