Eosinophils and Th2 immunity: contemporary insights
| Title: | Eosinophils and Th2 immunity: contemporary insights |
| Author: |
Spencer, Lisa Ann; Weller, Peter Fahey
Note: Order does not necessarily reflect citation order of authors. |
| Citation: | Spencer, Lisa A, and Peter F Weller. 2010. Eosinophils and Th2 Immunity: Contemporary Insights. Immunol Cell Biol 88, no. 3: 250–256. doi:10.1038/icb.2009.115. |
| Full Text & Related Files: |
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| Abstract: | Eosinophils, innate immune leukocytes elicited by Th2 cells, have long been associated with the effector arm of Th2 immune responses. However, accumulating data over the past decade reveal a much more dynamic picture of Th2 immunity, where eosinophils are present very early in response to Th2-inducing agents and function in the initiation of Th2 immunity. Here we discuss recent data showing immune functions of eosinophils distinct from their previously appreciated tissue- and helminth-destructive capacities, providing strong evidence for a new paradigm of Th2 immunity defined by a dynamic interplay between eosinophils and T cells. |
| Published Version: | doi:10.1038/icb.2009.115 |
| Other Sources: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589820/ |
| Terms of Use: | This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA |
| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:33730188 |
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