Late-Stage Deoxyfluorination of Alcohols with PhenoFluor
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CitationSladojevich, Filippo, Sophie I. Arlow, Pingping Tang, and Tobias Ritter. 2013. Late-Stage Deoxyfluorination of Alcohols with PhenoFluor. Journal of the American Chemical Society 135, no. 7: 2470–2473.
AbstractAn operationally simple protocol for the selective deoxyfluorination of structurally complex alcohols is presented. Several fluorinated derivatives of natural products and pharmaceuticals have been prepared to showcase the potential of the method for late-stage diversification and its functional group compatibility. A series of simple guidelines for predicting the selectivity in substrates with multiple alcohols is given.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34222825
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