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dc.contributor.authorFarris, Alton B.
dc.contributor.authorLauwers, Gregory Y.
dc.contributor.authorFerry, Judith Ann
dc.contributor.authorZukerberg, Lawrence R.
dc.date.accessioned2017-10-20T21:06:11Z
dc.date.issued2008
dc.identifier.citationFarris, Alton B., Gregory Y. Lauwers, Judith A. Ferry, and Lawrence R. Zukerberg. 2008. “The Rectal Tonsil: A Reactive Lymphoid Proliferation That May Mimic Lymphoma.” The American Journal of Surgical Pathology 32 (7) (July): 1075–1079. doi:10.1097/pas.0b013e318162c3ec.en_US
dc.identifier.issn0147-5185en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34268568
dc.description.abstractThe rectal tonsil (RT), a localized reactive proliferation of lymphoid tissue occurring in the rectum, can cause diagnostic difficulty; and awareness of this entity can prevent a misdiagnosis of lymphoma. A clinicopathologic analysis of 11 cases of RT was performed to determine the features that can aid in the recognition of this entity. The patients (6 males and 5 females) were middle-aged adults, except for 1 case affecting a young boy (age range, 1 to 62 y; mean, 49 y). All presented with either rectal bleeding or abdominal pain, or had the lesion found on routine screening. Endoscopic descriptions, available in all cases, reported a raised, polypoid lesion in 8 cases, a nodule in 2 cases, and a "mass" in 1 case. Histologically, all cases were composed of a lymphoid proliferation involving the lamina propria or submucosa. Lymphoid follicles could be identified in all cases, although some were difficult to appreciate without immunostains for follicular dendritic cells. Five cases showed overlying cryptitis and mild architectural distortion, but no cases showed crypt obliteration or crypt abscesses. Intraepithelial lymphocytes were present in 9 cases, and 5 cases showed nondestructive lymphoepithelial lesions. During a mean follow-up of 5.8 years, none showed a recurrence or developed lymphoma. In conclusion, RT, with its distinctive features, is an important entity to recognize. Familiarity with the range of histologic features characteristic of the RT is critical in avoiding misinterpretation as lymphoma.en_US
dc.language.isoen_USen_US
dc.publisherOvid Technologies (Wolters Kluwer Health)en_US
dc.relation.isversionofdoi:10.1097/PAS.0b013e318162c3ecen_US
dash.licenseMETA_ONLY
dc.subjectrectal tonsilen_US
dc.subjectlymphoid hyperplasiaen_US
dc.subjectlymphomaen_US
dc.subjectlymphoid follicular proctitisen_US
dc.subjectlymphoid polypen_US
dc.subjectrectumen_US
dc.titleThe Rectal Tonsil: A Reactive Lymphoid Proliferation That May Mimic Lymphomaen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalThe American Journal of Surgical Pathologyen_US
dash.depositing.authorLauwers, Gregory Y.
dash.embargo.until10000-01-01
dc.identifier.doi10.1097/PAS.0b013e318162c3ec*
workflow.legacycommentsnoap.darken_US
dash.contributor.affiliatedZukerberg, Lawrence
dash.contributor.affiliatedFerry, Judith
dash.contributor.affiliatedLauwers, Gregory Y.


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