Plasmapheresis for treatment of immune complex-mediated glomerulonephritis in infective endocarditis: a case report and literature review

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Plasmapheresis for treatment of immune complex-mediated glomerulonephritis in infective endocarditis: a case report and literature review

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Title: Plasmapheresis for treatment of immune complex-mediated glomerulonephritis in infective endocarditis: a case report and literature review
Author: Halpin, Meredith; Kozyreva, Olga; Bijol, Vanesa; Jaber, Bertrand L.

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Citation: Halpin, Meredith, Olga Kozyreva, Vanesa Bijol, and Bertrand L. Jaber. 2017. “Plasmapheresis for treatment of immune complex-mediated glomerulonephritis in infective endocarditis: a case report and literature review.” Clinical Nephrology. Case Studies 5 (1): 26-31. doi:10.5414/CNCS109082. http://dx.doi.org/10.5414/CNCS109082.
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Abstract: We report the case of a 57-year-old man who presented with subacute bacterial endocarditis secondary to Streptococcus mutans complicated by biopsy-proven immune complex-mediated glomerulonephritis (ICGN). Despite initial treatment with antibiotics and a short course of corticosteroids, the kidney function further deteriorated, and plasmapheresis was introduced as third-line therapy to remove circulating immune complexes. Following 7 treatment sessions, the patient recovered kidney function. We discuss the potential merit of plasmapheresis for patients with subacute bacterial endocarditis who develop ICGN.
Published Version: doi:10.5414/CNCS109082
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438014/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:34492251
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