Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons

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Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons

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Title: Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons
Author: Chew, Yee Lian; Walker, Denise S.; Towlson, Emma K.; Vértes, Petra E.; Yan, Gang; Barabási, Albert-László; Schafer, William R.

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Citation: Chew, Yee Lian, Denise S. Walker, Emma K. Towlson, Petra E. Vértes, Gang Yan, Albert-László Barabási, and William R. Schafer. 2017. “Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons.” Scientific Data 4 (1): 170156. doi:10.1038/sdata.2017.156. http://dx.doi.org/10.1038/sdata.2017.156.
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Abstract: Lesioning studies have provided important insight into the functions of brain regions in humans and other animals. In the nematode Caenorhabditis elegans, with a small nervous system of 302 identified neurons, it is possible to generate lesions with single cell resolution and infer the roles of individual neurons in behaviour. Here we present a dataset of ~300 video recordings representing the locomotor behaviour of animals carrying single-cell ablations of 5 different motorneurons. Each file includes a raw video of approximately 27,000 frames; each frame has also been segmented to yield the position, contour, and body curvature of the tracked animal. These recordings can be further analysed using publicly-available software to extract features relevant to behavioural phenotypes. This dataset therefore represents a useful resource for probing the neural basis of behaviour in C. elegans, a resource we hope to augment in the future with ablation recordings for additional neurons.
Published Version: doi:10.1038/sdata.2017.156
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647482/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:34492258
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