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dc.contributor.authorCho, Chung-Hyunen_US
dc.contributor.authorWoo, Jin Seoken_US
dc.contributor.authorPerez, Claudio Fen_US
dc.contributor.authorLee, Eun Huien_US
dc.date.accessioned2017-12-06T05:55:03Z
dc.date.issued2017en_US
dc.identifier.citationCho, Chung-Hyun, Jin Seok Woo, Claudio F Perez, and Eun Hui Lee. 2017. “A focus on extracellular Ca2+ entry into skeletal muscle.” Experimental & Molecular Medicine 49 (9): e378. doi:10.1038/emm.2017.208. http://dx.doi.org/10.1038/emm.2017.208.en
dc.identifier.issnen
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34492393
dc.description.abstractThe main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca2+ in the cytosol has a critical role in activating and deactivating a series of contractile proteins. In skeletal muscle, the cytosolic Ca2+ level is mainly determined by Ca2+ movements between the cytosol and the sarcoplasmic reticulum. The importance of Ca2+ entry from extracellular spaces to the cytosol has gained significant attention over the past decade. Store-operated Ca2+ entry with a low amplitude and relatively slow kinetics is a main extracellular Ca2+ entryway into skeletal muscle. Herein, recent studies on extracellular Ca2+ entry into skeletal muscle are reviewed along with descriptions of the proteins that are related to extracellular Ca2+ entry and their influences on skeletal muscle function and disease.en
dc.language.isoen_USen
dc.publisherNature Publishing Groupen
dc.relation.isversionofdoi:10.1038/emm.2017.208en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628281/pdf/en
dash.licenseLAAen_US
dc.titleA focus on extracellular Ca2+ entry into skeletal muscleen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalExperimental & Molecular Medicineen
dash.depositing.authorPerez, Claudio Fen_US
dc.date.available2017-12-06T05:55:03Z
dc.identifier.doi10.1038/emm.2017.208*
dash.contributor.affiliatedPerez, Claudio


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