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dc.contributor.authorSchaumberg, Debra Ann
dc.contributor.authorDana, Reza
dc.contributor.authorBuring, Julie Elizabeth
dc.contributor.authorSullivan, David A.
dc.date.accessioned2018-01-23T18:40:31Z
dc.date.issued2009
dc.identifierQuick submit: 2017-06-18T19:38:06-0400
dc.identifier.citationSchaumberg, Debra Ann, Reza Dana, Julie E. Buring, David A. Sullivan. 2009. Prevalence of Dry Eye Disease Among US Men: Estimates From the Physicians’ Health Studies. Arch Ophthalmology 127, no. 6 (2009): 763-68. doi: 10.1001/archophthalmol.2009.103en_US
dc.identifier.issn0003-9950en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34721616
dc.description.abstractObjective To estimate the prevalence and risk factors for dry eye disease (DED) among US men. Methods Cross-sectional prevalence survey among male participants 50 years and older in the Physicians' Health Studies I (N = 18 596) and II (N = 6848). We defined DED as the presence of clinically diagnosed dry eye or severe symptoms (both dryness and irritation constantly or often). We calculated the age-standardized prevalence of DED adjusted to the age distribution of US men in 2004 and projected estimates forward to 2030. We compared DED prevalence with a similar cohort of women and examined associations with possible risk factors. Results The prevalence of DED increased with age, from 3.90% among men aged 50 to 54 years to 7.67% among men 80 years and older (Pfor trend <.001). High blood pressure (odds ratio, 1.28; 95% confidence interval, 1.12-1.45) and benign prostatic hyperplasia (odds ratio, 1.26; 95% confidence interval, 1.09-1.44) were associated with a higher risk of DED. Use of antidepressants, antihypertensives, and medications to treat benign prostatic hyperplasia were also associated with increased risk of DED. The age-standardized prevalence of DED was 4.34%, or 1.68 million men 50 years and older, and is expected to affect more than 2.79 million US men by 2030. Conclusions Dry eye disease is prevalent and increases with age, hypertension, benign prostatic hyperplasia, and antidepressant use.en_US
dc.language.isoen_USen_US
dc.publisherAmerican Medical Association (AMA)en_US
dc.relation.isversionof10.1001/archophthalmol.2009.103en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836718/en_US
dash.licenseMETA_ONLY
dc.titlePrevalence of Dry Eye Disease Among US Menen_US
dc.typeJournal Articleen_US
dc.date.updated2017-06-18T23:38:07Z
dc.description.versionAccepted Manuscripten_US
dc.relation.journalArchives of Ophthalmologyen_US
dash.depositing.authorDana, Reza
dash.embargo.until10000-01-01
dc.date.available2009
dc.identifier.doi10.1001/archophthalmol.2009.103*
workflow.legacycommentscat.completeen_US
dash.contributor.affiliatedSullivan, David
dash.contributor.affiliatedSchaumberg, Debra A.
dash.contributor.affiliatedBuring, Julie
dash.contributor.affiliatedDana, Reza


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