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dc.contributor.authorLinnen, Catherine Ramsay
dc.contributor.authorHoekstra, Hopi E.
dc.date.accessioned2018-01-23T20:10:23Z
dc.date.issued2009
dc.identifierQuick submit: 2014-07-12T11:22:08-04:00
dc.identifier.citationLinnen, C. R., and H. E. Hoekstra. 2009. Measuring Natural Selection on Genotypes and Phenotypes in the Wild. Cold Spring Harbor Symposia on Quantitative Biology 74: 155–168. doi:10.1101/sqb.2009.74.045.en_US
dc.identifier.issn0091-7451en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34723157
dc.description.abstractA complete understanding of the role of natural selection in driving evolutionary change requires accurate estimates of the strength of selection acting in the wild. Accordingly, several approaches using a variety of data—including patterns of DNA variability, spatial and temporal changes in allele frequencies, and fitness estimates—have been developed to identify and quantify selection on both genotypes and phenotypes. Here, we review these approaches, drawing on both recent and classic examples to illustrate their utility and limitations. We then argue that by combining estimates of selection at multiple levels—from individual mutations to phenotypes—and at multiple timescales—from ecological to evolutionary—with experiments that demonstrate why traits are under selection, we can gain a much more complete picture of the adaptive process.en_US
dc.description.sponsorshipOrganismic and Evolutionary Biologyen_US
dc.language.isoen_USen_US
dc.publisherCold Spring Harbor Laboratory Pressen_US
dc.relation.isversionofdoi:10.1101/sqb.2009.74.045en_US
dash.licenseMETA_ONLY
dc.titleMeasuring Natural Selection on Genotypes and Phenotypes in the Wilden_US
dc.typeJournal Articleen_US
dc.date.updated2014-07-12T15:22:09Z
dc.description.versionVersion of Recorden_US
dc.rights.holderLinnen, C.R. and H.E. Hoekstra
dc.relation.journalCold Spring Harbor Symposia on Quantitative Biologyen_US
dash.depositing.authorHoekstra, Hopi E.
dash.embargo.until10000-01-01
dc.identifier.doi10.1101/sqb.2009.74.045*
workflow.legacycommentsoap.needman (MM) Hoekstra emailed 2016-05-15 MM Hoekstra emailed 2017-03-02 MMen_US
dash.contributor.affiliatedHoekstra, Hopi
dash.contributor.affiliatedLinnen, Catherine


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